{"title":"In Stock","description":"","products":[{"product_id":"sindbis-tr339-chikungunya-la-reunion-chimeric-virus","title":"Sindbis (TR339)\/Chikungunya (La Réunion) Chimeric Virus","description":"\u003cp\u003e\u003cb\u003eDescription:\u003c\/b\u003e This virus is a chimeric alphavirus containing the non-structural proteins of Sindbis virus (SINV) strain TR339 and the structural proteins from Chikungunya virus (CHIKV) strain La Réunion (LR) 2006-OPY1. This product allows the study of CHIKV LR 2006-OPY1 in a BSL-2 laboratory setting.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eStrain History:\u003c\/b\u003e TR339 is the consensus wild-type strain of SINV derived from the prototype AR339 isolate (\u003ci\u003eCulex\u003c\/i\u003e spp. mosquitoes, Egypt, 1952). The genomic sequence is \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nuccore\/2628941972\"\u003eavailable in NCBI\u003c\/a\u003e. CHIKV strain LR 2006-OPY1 was isolated from human serum collected from travelers returning from La Réunion island in 2006. The genomic sequence is \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nuccore\/DQ443544.2\"\u003eavailable in NCBI\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003ePassage History:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSINV TR339: Suckling mouse brain (8). References (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/13259009\/\"\u003e1\u003c\/a\u003e) and (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC190027\/\"\u003e2\u003c\/a\u003e).\u003c\/li\u003e\n\u003cli\u003eCHIKV LR 2006-OPY1: Vero E6 (unknown). Reference (\u003ca href=\"https:\/\/wwwnc.cdc.gov\/eid\/article\/12\/10\/06-0610_article\"\u003e3\u003c\/a\u003e).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eProduction:\u003c\/b\u003e Transfection of \u003ci\u003ein vitro\u003c\/i\u003e transcribed viral genomic RNA into baby hamster kidney (BHK) cells. No serial passages performed.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eBiosafety Level:\u003c\/b\u003e 2\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTiter:\u003c\/b\u003e 6.16 x 10\u003csup\u003e7\u003c\/sup\u003e PFU\/mL on BHK cells.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e 1.0 mL\/vial. Clarified and filtered cell culture supernatant frozen at -80°C. Delivered on dry ice.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eQA\/QC:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eTiter in PFU\/mL by plaque assay\u003c\/li\u003e\n\u003cli\u003eGenome equivalents\/mL by qPCR\u003c\/li\u003e\n\u003cli\u003eWhole-genome sequencing by NGS\u003c\/li\u003e\n\u003cli\u003eMycoplasma test by PCR\u003c\/li\u003e\n\u003cli\u003eSterility test for bacterial and fungal contamination\u003c\/li\u003e\n\u003cli\u003eEndotoxin test \u0026lt;10 EU\/mL\u003c\/li\u003e\n\u003cli\u003eDocumentation: Experimental conditions for QC tests, documentation of all reagents used.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eShipping:\u003c\/b\u003e As this product is a Sindbis virus derivative, customers must submit a USDA APHIS permit VS 16-3 to Advanced Virology prior to order shipment. The permit and additional information are available at \u003ca href=\"https:\/\/www.aphis.usda.gov\/animal-product-import\/organisms-vectors\"\u003eUSDA APHIS Permits\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003e\u003cu\u003eProduction Batch Information links (downloadable):\u003c\/u\u003e\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VC-004_2025-01_Certificate_of_Analysis_v.final.pdf?v=1757882764\"\u003eCertificate of Analysis\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href='https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VC-004_2025-01_Sequencing_Results_v.final.pdf?v=1757882814\"'\u003eNGS Results and Complete Genome Sequence\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href='https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VC-004_2025-01_Compiled_Batch_Record_v.final.pdf?v=1757882862\"'\u003eBatch Record: Detailed Production and QC Data\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href='https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV_Product_Use_Policy_04.10.2025.pdf.pdf?v=1746046086\"' rel=\"noopener\" target=\"_blank\"\u003eProduct Use Policy and Material Transfer Agreement\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Formats:\u003c\/b\u003e This product can be made as a purified or inactivated virus stock, or as purified viral genomic material. Many different reporter proteins and molecular tags can be incorporated. \u003ca href=\"%E2%80%9Dhttps:\/\/advancedvirology.com\/pages\/made-to-order-viruses%E2%80%9D\"\u003eCustom variant design and production services\u003c\/a\u003e are also available. Please \u003ca href=\"%E2%80%9Dhttps:\/\/advancedvirology.com\/pages\/contact-us%E2%80%9D\"\u003econtact us\u003c\/a\u003e for additional information.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Strains:\u003c\/b\u003e If you require a strain of this virus not listed on our website, please \u003ca href=\"%E2%80%9Dhttps:\/\/advancedvirology.com\/pages\/contact-us%E2%80%9D\"\u003econtact us\u003c\/a\u003e. We can produce a wide range of common strains to meet your needs.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Viruses Available:\u003c\/b\u003e If you are looking for a virus species or strain not listed on our website, please \u003ca href=\"%E2%80%9Dhttps:\/\/advancedvirology.com\/pages\/contact-us%E2%80%9D\"\u003econtact us\u003c\/a\u003e with your request. Our team of experts will work with you to create the product that meets your research needs and budget.\u003c\/p\u003e","brand":"Advanced Virology Inc.","offers":[{"title":"Default Title","offer_id":43963664138355,"sku":"AV-VC-004","price":450.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/Chimeric_Reporter.png?v=1764690563"},{"product_id":"sindbis-tr339-eastern-equine-encephalitis-fl93-939-chimeric-virus","title":"Sindbis (TR339)\/Eastern Equine Encephalitis (FL93-939) Chimeric Virus","description":"\u003cp\u003e\u003cb\u003eDescription:\u003c\/b\u003e This virus is a chimeric alphavirus containing the non-structural proteins of Sindbis virus (SINV) strain TR339 and the structural proteins from Eastern equine encephalitis virus (EEEV) strain FL93-939. This product allows the study of EEEV FL93-939 in a non-Select Agent BSL-2 laboratory setting.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eStrain History:\u003c\/b\u003e TR339 is the consensus wild-type strain of SINV derived from the prototype AR339 isolate (\u003ci\u003eCulex\u003c\/i\u003e spp. mosquitoes, Egypt, 1952). The genomic sequence is \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nuccore\/2628941972\"\u003eavailable in NCBI\u003c\/a\u003e. EEEV strain FL93-939 was isolated from an infected mosquito pool (\u003ci\u003eCuliseta melanura\u003c\/i\u003e) in Florida in 1993. The genomic sequence is \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nuccore\/119633046\"\u003eavailable in NCBI\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003ePassage History:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSINV TR339: Suckling mouse brain (8). References (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/13259009\/\"\u003e1\u003c\/a\u003e) and (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC190027\/\"\u003e2\u003c\/a\u003e).\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eEEEV FL93-939: Vero (Unknown), newborn mouse brain (1). References (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC2346730\/\"\u003e3\u003c\/a\u003e) and (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8827602\/\"\u003e4\u003c\/a\u003e).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eProduction:\u003c\/b\u003e Transfection of \u003ci\u003ein vitro\u003c\/i\u003e transcribed viral genomic RNA into baby hamster kidney (BHK) cells. No serial passages performed.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eBiosafety Level:\u003c\/b\u003e 2\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTiter:\u003c\/b\u003e 1.78 x 10\u003csup\u003e9\u003c\/sup\u003e PFU\/mL on BHK cells.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e 1.0 mL\/vial. Clarified and filtered cell culture supernatant frozen at -80°C. Delivered on dry ice.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eQA\/QC:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eTiter in PFU\/mL by plaque assay\u003c\/li\u003e\n\u003cli\u003eGenome equivalents\/mL by qPCR\u003c\/li\u003e\n\u003cli\u003eWhole-genome sequencing by NGS\u003c\/li\u003e\n\u003cli\u003eMycoplasma test by PCR\u003c\/li\u003e\n\u003cli\u003eSterility test for bacterial and fungal contamination\u003c\/li\u003e\n\u003cli\u003eEndotoxin test \u0026lt;10 EU\/mL\u003c\/li\u003e\n\u003cli\u003eDocumentation: Experimental conditions for QC tests, documentation of all reagents used.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eShipping:\u003c\/b\u003e As this product is a Sindbis virus derivative, customers must submit a USDA APHIS permit VS 16-3 to Advanced Virology prior to order shipment. The permit and additional information are available at \u003ca href=\"https:\/\/www.aphis.usda.gov\/animal-product-import\/organisms-vectors\"\u003eUSDA APHIS Permits\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003e\u003cu\u003eProduction Batch Information links (downloadable):\u003c\/u\u003e\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VC-002_2025-01_Certificate_of_Analysis_v.final.pdf?v=1757881400\"\u003eCertificate of Analysis\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VC-002_2025-01_Sequencing_Results_v.final.pdf?v=1757881434\"\u003eNGS Results and Complete Genome Sequence\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VC-002_2025-01_Compiled_Batch_Record_v.final.pdf?v=1757881464\"\u003eBatch Record: Detailed Production and QC Data\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV_Product_Use_Policy_04.10.2025.pdf.pdf?v=1746046086\" target=\"_blank\"\u003eProduct Use Policy and Material Transfer Agreement\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Formats:\u003c\/b\u003e This product can be made as a purified or inactivated virus stock, or as purified viral genomic material. Many different reporter proteins and molecular tags can be incorporated. \u003ca href=\"https:\/\/advancedvirology.com\/pages\/made-to-order-viruses\"\u003eCustom variant design and production services\u003c\/a\u003e are also available. Please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e for additional information.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Strains:\u003c\/b\u003e If you require a strain of this virus not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e. We can produce a wide range of common strains to meet your needs.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Viruses Available:\u003c\/b\u003e If you are looking for a virus species or strain not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e with your request. Our team of experts will work with you to create the product that meets your research needs and budget.\u003c\/p\u003e","brand":"Advanced Virology Inc.","offers":[{"title":"Default Title","offer_id":43963664892019,"sku":"AV-VC-002","price":450.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/Chimeric_Reporter.png?v=1764690563"},{"product_id":"sindbis-tr339-eastern-equine-encephalitis-fl93-939-chimeric-virus-egfp-reporter","title":"Sindbis (TR339)\/Eastern Equine Encephalitis (FL93-939) Chimeric Virus eGFP Reporter","description":"\u003cp\u003e\u003cb\u003eDescription:\u003c\/b\u003e This virus is a chimeric alphavirus containing the non-structural proteins of Sindbis virus (SINV) strain TR339 and the structural proteins from Eastern equine encephalitis virus (EEEV) strain FL93-939. In addition, this virus expresses the reporter protein eGFP at very high levels with minimal effect on viral replication or virulence. This product allows the study of EEEV FL93-939 in a non-Select Agent BSL-2 laboratory setting.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eStrain History:\u003c\/b\u003e TR339 is the consensus wild-type strain of SINV derived from the prototype AR339 isolate (\u003ci\u003eCulex\u003c\/i\u003e spp. mosquitoes, Egypt, 1952). The genomic sequence is \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nuccore\/2628941972\"\u003eavailable in NCBI\u003c\/a\u003e. EEEV strain FL93-939 was isolated from an infected mosquito pool (\u003ci\u003eCuliseta melanura\u003c\/i\u003e) in Florida in 1993. The genomic sequence is \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nuccore\/119633046\"\u003eavailable in NCBI\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003ePassage History:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSINV TR339: Suckling mouse brain (8). References (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/13259009\/\"\u003e1\u003c\/a\u003e) and (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC190027\/\"\u003e2\u003c\/a\u003e).\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eEEEV FL93-939: Vero (Unknown), newborn mouse brain (1). References (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC2346730\/\"\u003e3\u003c\/a\u003e) and (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8827602\/\"\u003e4\u003c\/a\u003e).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eProduction:\u003c\/b\u003e Transfection of \u003ci\u003ein vitro\u003c\/i\u003e transcribed viral genomic RNA into baby hamster kidney (BHK) cells. No serial passages performed.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eBiosafety Level:\u003c\/b\u003e 2\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTiter:\u003c\/b\u003e 1.58 x 10\u003csup\u003e9\u003c\/sup\u003e PFU\/mL on BHK cells.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e 1.0 mL\/vial. Clarified and filtered cell culture supernatant frozen at -80°C. Delivered on dry ice.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eQA\/QC:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eTiter in PFU\/mL by plaque assay\u003c\/li\u003e\n\u003cli\u003eGenome equivalents\/mL by qPCR\u003c\/li\u003e\n\u003cli\u003eWhole-genome sequencing by NGS\u003c\/li\u003e\n\u003cli\u003eMycoplasma test by PCR\u003c\/li\u003e\n\u003cli\u003eSterility test for bacterial and fungal contamination\u003c\/li\u003e\n\u003cli\u003eEndotoxin test \u0026lt;10 EU\/mL\u003c\/li\u003e\n\u003cli\u003eDocumented expression of eGFP reporter protein\u003c\/li\u003e\n\u003cli\u003eDocumentation: Experimental conditions for QC tests, documentation of all reagents used.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eReporter Virus Construction:\u003c\/b\u003e Reporter protein coding sequences were inserted between the capsid and PE2 loci and contain the 2A-like protease sequence from the Thosea asigna virus (TaV site) at the 3’ end. Upon polyprotein translation in infected cells, the capsid autoprotease domain and the TaV protease cleave the reporter protein from the capsid, resulting in reporter expression independent of incorporation into the virus particle. For additional information, see \u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3911548\/\"\u003ereference\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eShipping:\u003c\/b\u003e As this product is a Sindbis virus derivative, customers must submit a USDA APHIS permit VS 16-3 to Advanced Virology prior to order shipment. The permit and additional information are available at \u003ca href=\"https:\/\/www.aphis.usda.gov\/animal-product-import\/organisms-vectors\"\u003eUSDA APHIS Permits\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003e\u003cu\u003eProduction Batch Information links (downloadable):\u003c\/u\u003e\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VCR-003_2025-01_Certificate_of_Analysis_v.final.pdf?v=1757892235\" target=\"_blank\"\u003eCertificate of Analysis\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VCR-003_2025-01_Sequencing_Results_v.final.pdf?v=1757892264\"\u003eNGS Results and Complete Genome Sequence\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VCR-003_2025-01_Compiled_Batch_Record_v.final.pdf?v=1757892301\"\u003eBatch Record: Detailed Production and QC Data\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV_Product_Use_Policy_04.10.2025.pdf.pdf?v=1746046086\" target=\"_blank\"\u003eProduct Use Policy and Material Transfer Agreement\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Formats:\u003c\/b\u003e This product can be made as a purified or inactivated virus stock, or as purified viral genomic material. Many different reporter proteins and molecular tags can be incorporated. \u003ca href=\"https:\/\/advancedvirology.com\/pages\/made-to-order-viruses\"\u003eCustom variant design and production services\u003c\/a\u003e are also available. Please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e for additional information.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Strains:\u003c\/b\u003e If you require a strain of this virus not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e. We can produce a wide range of common strains to meet your needs.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Viruses Available:\u003c\/b\u003e If you are looking for a virus species or strain not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e with your request. Our team of experts will work with you to create the product that meets your research needs and budget.\u003c\/p\u003e","brand":"Advanced Virology Inc.","offers":[{"title":"Default Title","offer_id":43963664924787,"sku":"AV-VCR-003","price":500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/Alphavirus_-_eGFP_Reporter-Chimeric.png?v=1764690198"},{"product_id":"sindbis-tr339-eastern-equine-encephalitis-fl93-939-chimeric-virus-nluc-reporter","title":"Sindbis (TR339)\/Eastern Equine Encephalitis (FL93-939) Chimeric Virus nLuc Reporter","description":"\u003cp\u003e\u003cb\u003eDescription:\u003c\/b\u003e This virus is a chimeric alphavirus containing the non-structural proteins of Sindbis virus (SINV) strain TR339 and the structural proteins from Eastern equine encephalitis virus (EEEV) strain FL93-939. In addition, this virus expresses the reporter protein nanoluciferase (nLuc) at very high levels with minimal effect on viral replication or virulence. This product allows the study of EEEV FL93-939 in a non-Select Agent BSL-2 laboratory setting.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eStrain History:\u003c\/b\u003e TR339 is the consensus wild-type strain of SINV derived from the prototype AR339 isolate (\u003ci\u003eCulex\u003c\/i\u003e spp. mosquitoes, Egypt, 1952). The genomic sequence is \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nuccore\/2628941972\"\u003eavailable in NCBI\u003c\/a\u003e. EEEV strain FL93-939 was isolated from an infected mosquito pool (\u003ci\u003eCuliseta melanura\u003c\/i\u003e) in Florida in 1993. The genomic sequence is \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nuccore\/119633046\"\u003eavailable in NCBI\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003ePassage History:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSINV TR339: Suckling mouse brain (8). References (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/13259009\/\"\u003e1\u003c\/a\u003e) and (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC190027\/\"\u003e2\u003c\/a\u003e).\u003c\/li\u003e\n\u003cli\u003eEEEV FL93-939: Vero (Unknown), newborn mouse brain (1). References (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC2346730\/\" style=\"font-size: 0.875rem;\"\u003e3\u003c\/a\u003e\u003cspan style=\"font-size: 0.875rem;\"\u003e) and (\u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8827602\/\" style=\"font-size: 0.875rem;\"\u003e4\u003c\/a\u003e\u003cspan style=\"font-size: 0.875rem;\"\u003e).\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eProduction:\u003c\/b\u003e Transfection of \u003ci\u003ein vitro\u003c\/i\u003e transcribed viral genomic RNA into baby hamster kidney (BHK) cells. No serial passages performed.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eBiosafety Level:\u003c\/b\u003e 2\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTiter:\u003c\/b\u003e At least 2.10 x 10\u003csup\u003e9\u003c\/sup\u003e PFU\/mL on BHK cells.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e 1.0 mL\/vial. Clarified and filtered cell culture supernatant frozen at -80°C. Delivered on dry ice.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eQA\/QC:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eTiter in PFU\/mL by plaque assay\u003c\/li\u003e\n\u003cli\u003eGenome equivalents\/mL by qPCR\u003c\/li\u003e\n\u003cli\u003eWhole-genome sequencing by NGS\u003c\/li\u003e\n\u003cli\u003eMycoplasma test by PCR\u003c\/li\u003e\n\u003cli\u003eSterility test for bacterial and fungal contamination\u003c\/li\u003e\n\u003cli\u003eEndotoxin test \u0026lt;10 EU\/mL\u003c\/li\u003e\n\u003cli\u003eDocumented expression of nLuc reporter protein\u003c\/li\u003e\n\u003cli\u003eDocumentation: Experimental conditions for QC tests, documentation of all reagents used.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eReporter Virus Construction:\u003c\/b\u003e Reporter protein coding sequences were inserted between the capsid and PE2 loci and contain the 2A-like protease sequence from the Thosea asigna virus (TaV site) at the 3’ end. Upon polyprotein translation in infected cells, the capsid autoprotease domain and the TaV protease cleave the reporter protein from the capsid, resulting in reporter expression independent of incorporation into the virus particle. For additional information, see \u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3911548\/\"\u003ereference\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eShipping:\u003c\/b\u003e As this product is a Sindbis virus derivative, customers must submit a USDA APHIS permit VS 16-3 to Advanced Virology prior to order shipment. The permit and additional information are available at \u003ca href=\"https:\/\/www.aphis.usda.gov\/animal-product-import\/organisms-vectors\"\u003eUSDA APHIS Permits\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003e\u003cu\u003eProduction Batch Information links (downloadable):\u003c\/u\u003e\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VCR-004_2025-01_Certificate_of_Analysis_v.final.pdf?v=1757892601\"\u003eCertificate of Analysis\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VCR-004_2025-01_Sequencing_Results_v.final.pdf?v=1757892630\"\u003eNGS Results and Complete Genome Sequence\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VCR-004_2025-01_Compiled_Batch_Record_v.final.pdf?v=1757892665\"\u003eBatch Record: Detailed Production and QC Data\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV_Product_Use_Policy_04.10.2025.pdf.pdf?v=1746046086\" target=\"_blank\"\u003eProduct Use Policy and Material Transfer Agreement\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Formats:\u003c\/b\u003e This product can be made as a purified or inactivated virus stock, or as purified viral genomic material. Many different reporter proteins and molecular tags can be incorporated. \u003ca href=\"https:\/\/advancedvirology.com\/pages\/made-to-order-viruses\"\u003eCustom variant design and production services\u003c\/a\u003e are also available. Please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e for additional information.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Strains:\u003c\/b\u003e If you require a strain of this virus not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e. We can produce a wide range of common strains to meet your needs.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Viruses Available:\u003c\/b\u003e If you are looking for a virus species or strain not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e with your request. Our team of experts will work with you to create the product that meets your research needs and budget.\u003c\/p\u003e","brand":"Advanced Virology Inc.","offers":[{"title":"Default Title","offer_id":43963664990323,"sku":"AV-VCR-004","price":500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/Alphavirus_-_Chimeric_and_Repoter_nLuc.png?v=1764690198"},{"product_id":"sindbis-tr339-venezuelan-equine-encephalitis-trinidad-donkey-chimeric-virus","title":"Sindbis (TR339)\/Venezuelan Equine Encephalitis (Trinidad Donkey) Chimeric Virus","description":"\u003cp\u003e\u003cb\u003eDescription:\u003c\/b\u003e This virus is a chimeric alphavirus containing the non-structural proteins of Sindbis virus (SINV) strain TR339 and the structural proteins from Venezuelan equine encephalitis virus (VEEV) strain Trinidad donkey (TrD). This product allows the study of VEEV TrD in a non-Select Agent BSL-2 laboratory setting.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eStrain History:\u003c\/b\u003e TR339 is the consensus wild-type strain of SINV derived from the prototype AR339 isolate (\u003ci\u003eCulex\u003c\/i\u003e spp. mosquitoes, Egypt, 1952). The genomic sequence is \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nuccore\/2628941972\"\u003eavailable in NCBI\u003c\/a\u003e. VEEV clade IA\/B epizootic strain Trinidad donkey (TrD) was isolated from the brain tissue of an infected donkey in Trinidad in 1943. The genomic sequence is \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nuccore\/L01442.2\"\u003eavailable in NCBI\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003ePassage History:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSINV TR339: Suckling mouse brain (8). References (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/13259009\/\"\u003e1\u003c\/a\u003e) and (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC190027\/\"\u003e2\u003c\/a\u003e).\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eVEEV TrD: Guinea pigs (1), Vero (6), BHK (1). Reference (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6784384\/\"\u003e3\u003c\/a\u003e).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eProduction:\u003c\/b\u003e Transfection of \u003ci\u003ein vitro\u003c\/i\u003e transcribed viral genomic RNA into baby hamster kidney (BHK) cells. No serial passages performed.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eBiosafety Level:\u003c\/b\u003e 2\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTiter:\u003c\/b\u003e 1.20 x 10\u003csup\u003e7\u003c\/sup\u003e PFU\/mL on BHK cells.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e 1.0 mL\/vial. Clarified and filtered cell culture supernatant frozen at -80°C. Delivered on dry ice.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eQA\/QC:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eTiter in PFU\/mL by plaque assay\u003c\/li\u003e\n\u003cli\u003eGenome equivalents\/mL by qPCR\u003c\/li\u003e\n\u003cli\u003eWhole-genome sequencing by NGS\u003c\/li\u003e\n\u003cli\u003eMycoplasma test by PCR\u003c\/li\u003e\n\u003cli\u003eSterility test for bacterial and fungal contamination\u003c\/li\u003e\n\u003cli\u003eEndotoxin test \u0026lt;10 EU\/mL\u003c\/li\u003e\n\u003cli\u003eDocumentation: Experimental conditions for QC tests, documentation of all reagents used.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eShipping:\u003c\/b\u003e As this product is a Sindbis virus derivative, customers must submit a USDA APHIS permit VS 16-3 to Advanced Virology prior to order shipment. The permit and additional information are available at \u003ca href=\"https:\/\/www.aphis.usda.gov\/animal-product-import\/organisms-vectors\"\u003eUSDA APHIS Permits\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003e\u003cu\u003eProduction Batch Information links (downloadable):\u003c\/u\u003e\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VC-001_2025-01_-_Certificate_of_Analysis_v.final.pdf?v=1757880414\"\u003eCertificate of Analysis\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VC-001_2025-01_-_Sequencing_Results_v.final.pdf?v=1757880471\"\u003eNGS Results and Complete Genome Sequence\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VC-001_2025-01_-_Compiled_Batch_Record_v.final.pdf?v=1757880529\"\u003eBatch Record: Detailed Production and QC Data\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV_Product_Use_Policy_04.10.2025.pdf.pdf?v=1746046086\" target=\"_blank\"\u003eProduct Use Policy and Material Transfer Agreement\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Formats:\u003c\/b\u003e This product can be made as a purified or inactivated virus stock, or as purified viral genomic material. Many different reporter proteins and molecular tags can be incorporated. \u003ca href=\"https:\/\/advancedvirology.com\/pages\/made-to-order-viruses\"\u003eCustom variant design and production services\u003c\/a\u003e are also available. Please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e for additional information.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Strains:\u003c\/b\u003e If you require a strain of this virus not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e. We can produce a wide range of common strains to meet your needs.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Viruses Available:\u003c\/b\u003e If you are looking for a virus species or strain not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e with your request. Our team of experts will work with you to create the product that meets your research needs and budget.\u003c\/p\u003e","brand":"Advanced Virology Inc.","offers":[{"title":"Default Title","offer_id":43963665154163,"sku":"AV-VC-001","price":450.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/Chimeric_Reporter.png?v=1764690563"},{"product_id":"sindbis-tr339-venezuelan-equine-encephalitis-trinidad-donkey-chimeric-virus-egfp-reporter","title":"Sindbis (TR339)\/Venezuelan Equine Encephalitis (Trinidad Donkey) Chimeric Virus eGFP Reporter","description":"\u003cp\u003e\u003cb\u003eDescription:\u003c\/b\u003e This virus is a chimeric alphavirus containing the non-structural proteins of Sindbis virus (SINV) strain TR339 and the structural proteins from Venezuelan equine encephalitis virus (VEEV) strain Trinidad donkey (TrD). In addition, this virus expresses the reporter protein eGFP at very high levels with minimal effect on viral replication or virulence. This product allows the study of VEEV TrD in a non-Select Agent BSL-2 laboratory setting.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eStrain History:\u003c\/b\u003e TR339 is the consensus wild-type strain of SINV derived from the prototype AR339 isolate (\u003ci\u003eCulex\u003c\/i\u003e spp. mosquitoes, Egypt, 1952). The genomic sequence is \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nuccore\/2628941972\"\u003eavailable in NCBI\u003c\/a\u003e. VEEV clade IA\/B epizootic strain Trinidad donkey (TrD) was isolated from the brain tissue of an infected donkey in Trinidad in 1943. The genomic sequence is \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nuccore\/L01442.2\"\u003eavailable in NCBI\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003ePassage History:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSINV TR339: Suckling mouse brain (8). References (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/13259009\/\"\u003e1\u003c\/a\u003e) and (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC190027\/\"\u003e2\u003c\/a\u003e).\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eVEEV TrD: Guinea pigs (1), Vero (6), BHK (1). Reference (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6784384\/\"\u003e3\u003c\/a\u003e).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eProduction:\u003c\/b\u003e Transfection of \u003ci\u003ein vitro\u003c\/i\u003e transcribed viral genomic RNA into baby hamster kidney (BHK) cells. No serial passages performed.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eBiosafety Level:\u003c\/b\u003e 2\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTiter:\u003c\/b\u003e 5.60 x 10\u003csup\u003e6\u003c\/sup\u003e PFU\/mL on BHK cells.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e 1.0 mL\/vial. Clarified and filtered cell culture supernatant frozen at -80°C. Delivered on dry ice.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eQA\/QC:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eTiter in PFU\/mL by plaque assay\u003c\/li\u003e\n\u003cli\u003eGenome equivalents\/mL by qPCR\u003c\/li\u003e\n\u003cli\u003eWhole-genome sequencing by NGS\u003c\/li\u003e\n\u003cli\u003eMycoplasma test by PCR\u003c\/li\u003e\n\u003cli\u003eSterility test for bacterial and fungal contamination\u003c\/li\u003e\n\u003cli\u003eEndotoxin test \u0026lt;10 EU\/mL\u003c\/li\u003e\n\u003cli\u003eDocumented expression of eGFP reporter protein\u003c\/li\u003e\n\u003cli\u003eDocumentation: Experimental conditions for QC tests, documentation of all reagents used.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eReporter Virus Construction:\u003c\/b\u003e Reporter protein coding sequences were inserted between the capsid and PE2 loci and contain the 2A-like protease sequence from the Thosea asigna virus (TaV site) at the 3’ end. Upon polyprotein translation in infected cells, the capsid autoprotease domain and the TaV protease cleave the reporter protein from the capsid, resulting in reporter expression independent of incorporation into the virus particle. For additional information, see \u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3911548\/\"\u003ereference\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eShipping:\u003c\/b\u003e As this product is a Sindbis virus derivative, customers must submit a USDA APHIS permit VS 16-3 to Advanced Virology prior to order shipment. The permit and additional information are available at \u003ca href=\"https:\/\/www.aphis.usda.gov\/animal-product-import\/organisms-vectors\"\u003eUSDA APHIS Permits\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003e\u003cu\u003eProduction Batch Information links (downloadable):\u003c\/u\u003e\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VCR-001_2025-01_Certificate_of_Analysis_v.final.pdf?v=1757883292\"\u003eCertificate of Analysis\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VCR-001_2025-01_Sequencing_Results_v.final.pdf?v=1757883324\"\u003eNGS Results and Complete Genome Sequence\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VCR-001_2025-01_Compiled_Batch_Record_v.final.pdf?v=1757883362\"\u003eBatch Record: Detailed Production and QC Data\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV_Product_Use_Policy_04.10.2025.pdf.pdf?v=1746046086\" target=\"_blank\"\u003eProduct Use Policy and Material Transfer Agreement\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Formats:\u003c\/b\u003e This product can be made as a purified or inactivated virus stock, or as purified viral genomic material. Many different reporter proteins and molecular tags can be incorporated. \u003ca href=\"https:\/\/advancedvirology.com\/pages\/made-to-order-viruses\"\u003eCustom variant design and production services\u003c\/a\u003e are also available. Please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e for additional information.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Strains:\u003c\/b\u003e If you require a strain of this virus not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e. We can produce a wide range of common strains to meet your needs.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Viruses Available:\u003c\/b\u003e If you are looking for a virus species or strain not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e with your request. Our team of experts will work with you to create the product that meets your research needs and budget.\u003c\/p\u003e","brand":"Advanced Virology Inc.","offers":[{"title":"Default Title","offer_id":43963665186931,"sku":"AV-VCR-001","price":500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/Alphavirus_-_eGFP_Reporter-Chimeric.png?v=1764690198"},{"product_id":"sindbis-tr339-venezuelan-equine-encephalitis-trinidad-donkey-chimeric-virus-nluc-reporter","title":"Sindbis (TR339)\/Venezuelan Equine Encephalitis (Trinidad Donkey) Chimeric Virus nLuc Reporter","description":"\u003cp\u003e\u003cb\u003eDescription:\u003c\/b\u003e This virus is a chimeric alphavirus containing the non-structural proteins of Sindbis virus (SINV) strain TR339 and the structural proteins from Venezuelan equine encephalitis virus (VEEV) strain Trinidad donkey (TrD). In addition, this virus expresses the reporter protein nanoluciferase (nLuc) at very high levels with minimal effect on viral replication or virulence. This product allows the study of VEEV TrD in a non-Select Agent BSL-2 laboratory setting.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eStrain History:\u003c\/b\u003e TR339 is the consensus wild-type strain of SINV derived from the prototype AR339 isolate (\u003ci\u003eCulex\u003c\/i\u003e spp. mosquitoes, Egypt, 1952). The genomic sequence is \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nuccore\/2628941972\"\u003eavailable in NCBI\u003c\/a\u003e. VEEV clade IA\/B epizootic strain Trinidad donkey (TrD) was isolated from the brain tissue of an infected donkey in Trinidad in 1943. The genomic sequence is \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nuccore\/L01442.2\"\u003eavailable in NCBI\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003ePassage History:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSINV TR339: Suckling mouse brain (8). References (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/13259009\/\"\u003e1\u003c\/a\u003e) and (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC190027\/\"\u003e2\u003c\/a\u003e).\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eVEEV TrD: Guinea pigs (1), Vero (6), BHK (1). Reference (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6784384\/\"\u003e3\u003c\/a\u003e).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eProduction:\u003c\/b\u003e Transfection of \u003ci\u003ein vitro\u003c\/i\u003e transcribed viral genomic RNA into baby hamster kidney (BHK) cells. No serial passages performed.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eBiosafety Level:\u003c\/b\u003e 2\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTiter:\u003c\/b\u003e 1.16 x 10\u003csup\u003e7\u003c\/sup\u003e PFU\/mL on BHK cells.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e 1.0 mL\/vial. Clarified and filtered cell culture supernatant frozen at -80°C. Delivered on dry ice.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eQA\/QC:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eTiter in PFU\/mL by plaque assay\u003c\/li\u003e\n\u003cli\u003eGenome equivalents\/mL by qPCR\u003c\/li\u003e\n\u003cli\u003eWhole-genome sequencing by NGS\u003c\/li\u003e\n\u003cli\u003eMycoplasma test by PCR\u003c\/li\u003e\n\u003cli\u003eSterility test for bacterial and fungal contamination\u003c\/li\u003e\n\u003cli\u003eEndotoxin test \u0026lt;10 EU\/mL\u003c\/li\u003e\n\u003cli\u003eDocumented expression of nLuc reporter protein\u003c\/li\u003e\n\u003cli\u003eDocumentation: Experimental conditions for QC tests, documentation of all reagents used.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eReporter Virus Construction:\u003c\/b\u003e Reporter protein coding sequences were inserted between the capsid and PE2 loci and contain the 2A-like protease sequence from the Thosea asigna virus (TaV site) at the 3’ end. Upon polyprotein translation in infected cells, the capsid autoprotease domain and the TaV protease cleave the reporter protein from the capsid, resulting in reporter expression independent of incorporation into the virus particle. For additional information, see \u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3911548\/\"\u003ereference\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eShipping:\u003c\/b\u003e As this product is a Sindbis virus derivative, customers must submit a USDA APHIS permit VS 16-3 to Advanced Virology prior to order shipment. The permit and additional information are available at \u003ca href=\"https:\/\/www.aphis.usda.gov\/animal-product-import\/organisms-vectors\"\u003eUSDA APHIS Permits\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003e\u003cu\u003eProduction Batch Information links (downloadable):\u003c\/u\u003e\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VCR-002_2025-01_Certificate_of_Analysis_v.final.pdf?v=1757891832\"\u003eCertificate of Analysis\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VCR-002_2025-01_Sequencing_Results_v.final.pdf?v=1757891864\"\u003eNGS Results and Complete Genome Sequence\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VCR-002_2025-01_Compiled_Batch_Record_v.final.pdf?v=1757891894\"\u003eBatch Record: Detailed Production and QC Data\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV_Product_Use_Policy_04.10.2025.pdf.pdf?v=1746046086\" target=\"_blank\"\u003eProduct Use Policy and Material Transfer Agreement\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Formats:\u003c\/b\u003e This product can be made as a purified or inactivated virus stock, or as purified viral genomic material. Many different reporter proteins and molecular tags can be incorporated. \u003ca href=\"https:\/\/advancedvirology.com\/pages\/made-to-order-viruses\"\u003eCustom variant design and production services\u003c\/a\u003e are also available. Please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e for additional information.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Strains:\u003c\/b\u003e If you require a strain of this virus not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e. We can produce a wide range of common strains to meet your needs.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Viruses Available:\u003c\/b\u003e If you are looking for a virus species or strain not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e with your request. Our team of experts will work with you to create the product that meets your research needs and budget.\u003c\/p\u003e","brand":"Advanced Virology Inc.","offers":[{"title":"Default Title","offer_id":43963665252467,"sku":"AV-VCR-002","price":500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/Alphavirus_-_Chimeric_and_Repoter_nLuc.png?v=1764690198"},{"product_id":"sindbis-tr339-western-equine-encephalitis-mcmillan-chimeric-virus-egfp-reporter","title":"Sindbis (TR339)\/Western Equine Encephalitis (McMillan) Chimeric Virus eGFP Reporter","description":"\u003cp\u003e\u003cb\u003eDescription:\u003c\/b\u003e This virus is a chimeric alphavirus containing the non-structural proteins of Sindbis virus (SINV) strain TR339 and the structural proteins from Western equine encephalitis virus (WEEV) strain McMillan. In addition, this virus expresses the reporter protein eGFP at very high levels with minimal effect on viral replication or virulence. This product allows the study of WEEV McMillan in a non-Select Agent BSL-2 laboratory setting.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eStrain History:\u003c\/b\u003e TR339 is the consensus wild-type strain of SINV derived from the prototype AR339 isolate (\u003ci\u003eCulex\u003c\/i\u003e spp. mosquitoes, Egypt, 1952). The genomic sequence is \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nuccore\/2628941972\"\u003eavailable in NCBI\u003c\/a\u003e. WEEV strain McMillan was isolated from an infected human in Ontario, Canada in 1941. The genomic sequence is \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nuccore\/254595918\"\u003eavailable in NCBI\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003ePassage History:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSINV TR339: Suckling mouse brain (8). References (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/13259009\/\"\u003e1\u003c\/a\u003e) and (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC190027\/\"\u003e2\u003c\/a\u003e).\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eWEEV McMillan: Mouse (2), Suckling mouse brain (1), Vero (2). Reference (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC2887574\/\"\u003e3\u003c\/a\u003e).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eProduction:\u003c\/b\u003e Transfection of \u003ci\u003ein vitro\u003c\/i\u003e transcribed viral genomic RNA into baby hamster kidney (BHK) cells. No serial passages performed.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eBiosafety Level:\u003c\/b\u003e 2\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTiter:\u003c\/b\u003e 1.06 x 10\u003csup\u003e7\u003c\/sup\u003e PFU\/mL on BHK cells.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e 1.0 mL\/vial. Clarified and filtered cell culture supernatant frozen at -80°C. Delivered on dry ice.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eQA\/QC:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eTiter in PFU\/mL by plaque assay\u003c\/li\u003e\n\u003cli\u003eGenome equivalents\/mL by qPCR\u003c\/li\u003e\n\u003cli\u003eWhole-genome sequencing by NGS\u003c\/li\u003e\n\u003cli\u003eMycoplasma test by PCR\u003c\/li\u003e\n\u003cli\u003eSterility test for bacterial and fungal contamination\u003c\/li\u003e\n\u003cli\u003eEndotoxin test \u0026lt;10 EU\/mL\u003c\/li\u003e\n\u003cli\u003eDocumented expression of eGFP reporter protein\u003c\/li\u003e\n\u003cli\u003eDocumentation: Experimental conditions for QC tests, documentation of all reagents used.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eReporter Virus Construction:\u003c\/b\u003e Reporter protein coding sequences were inserted between the capsid and PE2 loci and contain the 2A-like protease sequence from the Thosea asigna virus (TaV site) at the 3’ end. Upon polyprotein translation in infected cells, the capsid autoprotease domain and the TaV protease cleave the reporter protein from the capsid, resulting in reporter expression independent of incorporation into the virus particle. For additional information, see \u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3911548\/\"\u003ereference\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eShipping:\u003c\/b\u003e As this product is a Sindbis virus derivative, customers must submit a USDA APHIS permit VS 16-3 to Advanced Virology prior to order shipment. The permit and additional information are available at \u003ca href=\"https:\/\/www.aphis.usda.gov\/animal-product-import\/organisms-vectors\"\u003eUSDA APHIS Permits\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003e\u003cu\u003eProduction Batch Information links (downloadable):\u003c\/u\u003e\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VCR-006_2025-01_Certificate_of_Analysis_v.final.pdf?v=1757893468\"\u003eCertificate of Analysis\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VCR-006_2025-01_Sequencing_Results_v.final.pdf?v=1757893496\"\u003eNGS Results and Complete Genome Sequence\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VCR-006_2025-01_Compiled_Batch_Record_v.final.pdf?v=1757893529\"\u003eBatch Record: Detailed Production and QC Data\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV_Product_Use_Policy_04.10.2025.pdf.pdf?v=1746046086\" target=\"_blank\"\u003eProduct Use Policy and Material Transfer Agreement\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Formats:\u003c\/b\u003e This product can be made as a purified or inactivated virus stock, or as purified viral genomic material. Many different reporter proteins and molecular tags can be incorporated. \u003ca href=\"https:\/\/advancedvirology.com\/pages\/made-to-order-viruses\"\u003eCustom variant design and production services\u003c\/a\u003e are also available. Please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e for additional information.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Strains:\u003c\/b\u003e If you require a strain of this virus not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e. We can produce a wide range of common strains to meet your needs.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Viruses Available:\u003c\/b\u003e If you are looking for a virus species or strain not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e with your request. Our team of experts will work with you to create the product that meets your research needs and budget.\u003c\/p\u003e","brand":"Advanced Virology Inc.","offers":[{"title":"Default Title","offer_id":43963665449075,"sku":"AV-VCR-006","price":500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/Alphavirus_-_eGFP_Reporter-Chimeric.png?v=1764690198"},{"product_id":"sindbis-tr339-western-equine-encephalitis-mcmillan-chimeric-virus-nluc-reporter","title":"Sindbis (TR339)\/Western Equine Encephalitis (McMillan) Chimeric Virus nLuc Reporter","description":"\u003cp\u003e\u003cb\u003eDescription:\u003c\/b\u003e This virus is a chimeric alphavirus containing the non-structural proteins of Sindbis virus (SINV) strain TR339 and the structural proteins from Western equine encephalitis virus (WEEV) strain McMillan. In addition, this virus expresses the reporter protein nanoluciferase (nLuc) at very high levels with minimal effect on viral replication or virulence. This product allows the study of WEEV McMillan in a non-Select Agent BSL-2 laboratory setting.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eStrain History:\u003c\/b\u003e TR339 is the consensus wild-type strain of SINV derived from the prototype AR339 isolate (\u003ci\u003eCulex\u003c\/i\u003e spp. mosquitoes, Egypt, 1952). The genomic sequence is \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nuccore\/2628941972\"\u003eavailable in NCBI\u003c\/a\u003e. WEEV strain McMillan was isolated from an infected human in Ontario, Canada in 1941. The genomic sequence is \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nuccore\/254595918\"\u003eavailable in NCBI\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003ePassage History:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSINV TR339: Suckling mouse brain (8). References (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/13259009\/\"\u003e1\u003c\/a\u003e) and (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC190027\/\"\u003e2\u003c\/a\u003e).\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eWEEV McMillan: Mouse (2), Suckling mouse brain (1), Vero (2). Reference (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC2887574\/\"\u003e3\u003c\/a\u003e).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eProduction:\u003c\/b\u003e Transfection of \u003ci\u003ein vitro\u003c\/i\u003e transcribed viral genomic RNA into baby hamster kidney (BHK) cells. No serial passages performed.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eBiosafety Level:\u003c\/b\u003e 2\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTiter:\u003c\/b\u003e 1.02 x 10\u003csup\u003e7\u003c\/sup\u003e PFU\/mL on BHK cells.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e 1.0 mL\/vial. Clarified and filtered cell culture supernatant frozen at -80°C. Delivered on dry ice.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eQA\/QC:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eTiter in PFU\/mL by plaque assay\u003c\/li\u003e\n\u003cli\u003eGenome equivalents\/mL by qPCR\u003c\/li\u003e\n\u003cli\u003eWhole-genome sequencing by NGS\u003c\/li\u003e\n\u003cli\u003eMycoplasma test by PCR\u003c\/li\u003e\n\u003cli\u003eSterility test for bacterial and fungal contamination\u003c\/li\u003e\n\u003cli\u003eEndotoxin test \u0026lt;10 EU\/mL\u003c\/li\u003e\n\u003cli\u003eDocumented expression of nLuc reporter protein\u003c\/li\u003e\n\u003cli\u003eDocumentation: Experimental conditions for QC tests, documentation of all reagents used.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eReporter Virus Construction:\u003c\/b\u003e Reporter protein coding sequences were inserted between the capsid and PE2 loci and contain the 2A-like protease sequence from the Thosea asigna virus (TaV site) at the 3’ end. Upon polyprotein translation in infected cells, the capsid autoprotease domain and the TaV protease cleave the reporter protein from the capsid, resulting in reporter expression independent of incorporation into the virus particle. For additional information, see \u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3911548\/\"\u003ereference\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eShipping:\u003c\/b\u003e As this product is a Sindbis virus derivative, customers must submit a USDA APHIS permit VS 16-3 to Advanced Virology prior to order shipment. The permit and additional information are available at \u003ca href=\"https:\/\/www.aphis.usda.gov\/animal-product-import\/organisms-vectors\"\u003eUSDA APHIS Permits\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003e\u003cu\u003eProduction Batch Information links (downloadable):\u003c\/u\u003e\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VCR-007_2025-01_Certificate_of_Analysis_v.final.pdf?v=1757894137\"\u003eCertificate of Analysis\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VCR-007_2025-01_Sequencing_Results_v.final.pdf?v=1757894165\"\u003eNGS Results and Complete Genome Sequence\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VCR-007_2025-01_Compiled_Batch_Record_v.final.pdf?v=1757894194\"\u003eBatch Record: Detailed Production and QC Data\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV_Product_Use_Policy_04.10.2025.pdf.pdf?v=1746046086\" target=\"_blank\"\u003eProduct Use Policy and Material Transfer Agreement\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Formats:\u003c\/b\u003e This product can be made as a purified or inactivated virus stock, or as purified viral genomic material. Many different reporter proteins and molecular tags can be incorporated. \u003ca href=\"https:\/\/advancedvirology.com\/pages\/made-to-order-viruses\"\u003eCustom variant design and production services\u003c\/a\u003e are also available. Please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e for additional information.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Strains:\u003c\/b\u003e If you require a strain of this virus not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e. We can produce a wide range of common strains to meet your needs.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Viruses Available:\u003c\/b\u003e If you are looking for a virus species or strain not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e with your request. Our team of experts will work with you to create the product that meets your research needs and budget.\u003c\/p\u003e","brand":"Advanced Virology Inc.","offers":[{"title":"Default Title","offer_id":43963665514611,"sku":"AV-VCR-007","price":500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/Alphavirus_-_Chimeric_and_Repoter_nLuc.png?v=1764690198"},{"product_id":"sindbis-virus-strain-tr339-wild-type","title":"Sindbis virus strain TR339 - Wild Type","description":"\u003cp\u003e\u003cb\u003eDescription:\u003c\/b\u003e This is a wild-type alphavirus.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eStrain History:\u003c\/b\u003e TR339 is the consensus wild-type strain of Sindbis virus (SINV) derived from the prototype AR339 isolate (\u003ci\u003eCulex\u003c\/i\u003e spp. mosquitoes, Egypt, 1952). The genomic sequence is \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nuccore\/2628941972\"\u003eavailable in NCBI\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003ePassage History:\u003c\/b\u003e Suckling mouse brain (8). References (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/13259009\/\"\u003e1\u003c\/a\u003e) and (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC190027\/\"\u003e2\u003c\/a\u003e)\u003cbr\u003e\u003cbr\u003e\u003cb\u003eProduction:\u003c\/b\u003e Transfection of \u003ci\u003ein vitro\u003c\/i\u003e transcribed viral genomic RNA into baby hamster kidney (BHK) cells. No serial passages performed.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eBiosafety Level:\u003c\/b\u003e 2\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTiter:\u003c\/b\u003e 3.16 x 10\u003csup\u003e7\u003c\/sup\u003e TCID50\/mL on BHK cells.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e 1.0 mL\/vial. Clarified and filtered cell culture supernatant frozen at -80°C. Delivered on dry ice.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eQA\/QC:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eTiter in TCID50\/mL \u003c\/li\u003e\n\u003cli\u003eWhole-genome sequencing by NGS\u003c\/li\u003e\n\u003cli\u003eMycoplasma test by PCR\u003c\/li\u003e\n\u003cli\u003eSterility test for bacterial and fungal contamination\u003c\/li\u003e\n\u003cli\u003eEndotoxin test \u0026lt;0.25 EU\/mL\u003c\/li\u003e\n\u003cli\u003eDocumentation: Experimental conditions for QC tests\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cbr\u003e\u003cb\u003eShipping:\u003c\/b\u003e As this product is a Sindbis virus strain, customers must submit a USDA APHIS permit VS 16-3 to Advanced Virology prior to order shipment. The permit and additional information are available at \u003ca href=\"https:\/\/www.aphis.usda.gov\/animal-product-import\/organisms-vectors\"\u003eUSDA APHIS Permits\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003e\u003cu\u003eProduction Batch Information links (downloadable):\u003c\/u\u003e\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-V-008_-_Certificate_of_Analysis_-_Signed.pdf?v=1781011563\" rel=\"noopener\" target=\"_blank\"\u003eCertificate of Analysis\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca rel=\"noopener\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-V-008_-_Sequencing_Results.pdf?v=1781011563\" target=\"_blank\"\u003eNGS Results and Complete Genome Sequence\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-V-008_-_Batch_Record.pdf?v=1781011563\" target=\"_blank\" rel=\"noopener\"\u003eBatch Record: Detailed Production and QC Data\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV_Product_Use_Policy_04.10.2025.pdf.pdf?v=1746046086\" target=\"_blank\"\u003eProduct Use Policy and Material Transfer Agreement\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Formats:\u003c\/b\u003e This product can be made as a purified or inactivated virus stock, or as purified viral genomic material. Many different reporter proteins and molecular tags can be incorporated. \u003ca href=\"https:\/\/advancedvirology.com\/pages\/made-to-order-viruses\"\u003eCustom variant design and production services\u003c\/a\u003e are also available. Please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e for additional information.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Strains:\u003c\/b\u003e If you require a strain of this virus not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e. We can produce a wide range of common strains to meet your needs.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Viruses Available:\u003c\/b\u003e If you are looking for a virus species or strain not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e with your request. Our team of experts will work with you to create the product that meets your research needs and budget.\u003c\/p\u003e","brand":"Advanced Virology Inc.","offers":[{"title":"Default Title","offer_id":43963665547379,"sku":"AV-V-008","price":450.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/Alphavirus_-_Wild_Type.png?v=1764690198"},{"product_id":"sindbis-virus-strain-tr339-egfp-reporter","title":"Sindbis virus strain TR339 - eGFP Reporter","description":"\u003cp\u003e\u003cb\u003eDescription:\u003c\/b\u003e This alphavirus expresses the reporter protein eGFP at very high levels with minimal effect on viral replication or virulence.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eStrain History:\u003c\/b\u003e TR339 is the consensus wild-type strain of Sindbis virus (SINV) derived from the prototype AR339 isolate (\u003ci\u003eCulex\u003c\/i\u003e spp. mosquitoes, Egypt, 1952). The genomic sequence is \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nuccore\/2628941972\"\u003eavailable in NCBI\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003ePassage History:\u003c\/b\u003e Suckling mouse brain (8). References (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/13259009\/\"\u003e1\u003c\/a\u003e) and (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC190027\/\"\u003e2\u003c\/a\u003e)\u003cbr\u003e\u003cbr\u003e\u003cb\u003eProduction:\u003c\/b\u003e Transfection of \u003ci\u003ein vitro\u003c\/i\u003e transcribed viral genomic RNA into baby hamster kidney (BHK) cells. No serial passages performed.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eBiosafety Level:\u003c\/b\u003e 2\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTiter:\u003c\/b\u003e 3.16 x 10\u003csup\u003e7\u003c\/sup\u003e TCID50\/mL on BHK cells.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e 1.0 mL\/vial. Clarified and filtered cell culture supernatant frozen at -80°C. Delivered on dry ice.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eQA\/QC:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eTiter in TCID50\/mL \u003c\/li\u003e\n\u003cli\u003eWhole-genome sequencing by NGS\u003c\/li\u003e\n\u003cli\u003eMycoplasma test by PCR\u003c\/li\u003e\n\u003cli\u003eSterility test for bacterial and fungal contamination\u003c\/li\u003e\n\u003cli\u003eEndotoxin test \u0026lt;0.25 EU\/mL\u003c\/li\u003e\n\u003cli\u003eDocumentation: Experimental conditions for QC tests\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eReporter Virus Construction:\u003c\/b\u003e Reporter protein coding sequences were inserted between the capsid and PE2 loci and contain the 2A-like protease sequence from the Thosea asigna virus (TaV site) at the 3’ end. Upon polyprotein translation in infected cells, the capsid autoprotease domain and the TaV protease cleave the reporter protein from the capsid, resulting in reporter expression independent of incorporation into the virus particle. For additional information, see \u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3911548\/\"\u003ereference\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eShipping:\u003c\/b\u003e As this product is a Sindbis virus strain, customers must submit a USDA APHIS permit VS 16-3 to Advanced Virology prior to order shipment. The permit and additional information are available at \u003ca href=\"https:\/\/www.aphis.usda.gov\/animal-product-import\/organisms-vectors\"\u003eUSDA APHIS Permits\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003e\u003cu\u003eProduction Batch Information links (downloadable):\u003c\/u\u003e\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VR-015_-_Certificate_of_Analysis_-_Signed.pdf?v=1781020332\" rel=\"noopener\" target=\"_blank\"\u003eCertificate of Analysis\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca rel=\"noopener\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VR-015_-_Sequencing_Results.pdf?v=1781020331\" target=\"_blank\"\u003eNGS Results and Complete Genome Sequence\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VR-015_-_Batch_Record.pdf?v=1781020333\" target=\"_blank\" rel=\"noopener\"\u003eBatch Record: Detailed Production and QC Data\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV_Product_Use_Policy_04.10.2025.pdf.pdf?v=1746046086\" target=\"_blank\"\u003eProduct Use Policy and Material Transfer Agreement\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Formats:\u003c\/b\u003e This product can be made as a purified or inactivated virus stock, or as purified viral genomic material. Many different reporter proteins and molecular tags can be incorporated. \u003ca href=\"https:\/\/advancedvirology.com\/pages\/made-to-order-viruses\"\u003eCustom variant design and production services\u003c\/a\u003e are also available. Please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e for additional information.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Strains:\u003c\/b\u003e If you require a strain of this virus not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e. We can produce a wide range of common strains to meet your needs.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Viruses Available:\u003c\/b\u003e If you are looking for a virus species or strain not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e with your request. Our team of experts will work with you to create the product that meets your research needs and budget.\u003c\/p\u003e","brand":"Advanced Virology Inc.","offers":[{"title":"Default Title","offer_id":43963665580147,"sku":"AV-VR-015","price":500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/Alphavirus_-_eGFP_Reporter.png?v=1764690198"},{"product_id":"sindbis-virus-strain-tr339-mcherry-reporter","title":"Sindbis virus strain TR339 - mCherry Reporter","description":"\u003cp\u003e\u003cb\u003eDescription:\u003c\/b\u003e This alphavirus expresses the the reporter protein mCherry at very high levels with minimal effect on viral replication or virulence.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eStrain History:\u003c\/b\u003e TR339 is the consensus wild-type strain of Sindbis virus (SINV) derived from the prototype AR339 isolate (\u003ci\u003eCulex\u003c\/i\u003e spp. mosquitoes, Egypt, 1952). The genomic sequence is \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nuccore\/2628941972\"\u003eavailable in NCBI\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003ePassage History:\u003c\/b\u003e Suckling mouse brain (8). References (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/13259009\/\"\u003e1\u003c\/a\u003e) and (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC190027\/\"\u003e2\u003c\/a\u003e)\u003cbr\u003e\u003cbr\u003e\u003cb\u003eProduction:\u003c\/b\u003e Transfection of \u003ci\u003ein vitro\u003c\/i\u003e transcribed viral genomic RNA into baby hamster kidney (BHK) cells. No serial passages performed.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eBiosafety Level:\u003c\/b\u003e 2\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTiter:\u003c\/b\u003e 3.16 x 10\u003csup\u003e5\u003c\/sup\u003e TCID50\/mL on BHK cells.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e 1.0 mL\/vial. Clarified and filtered cell culture supernatant frozen at -80°C. Delivered on dry ice.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eQA\/QC:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eTiter in TCID50\/mL\u003c\/li\u003e\n\u003cli\u003eWhole-genome sequencing by NGS\u003c\/li\u003e\n\u003cli\u003eMycoplasma test by PCR\u003c\/li\u003e\n\u003cli\u003eSterility test for bacterial and fungal contamination\u003c\/li\u003e\n\u003cli\u003eEndotoxin test \u0026lt;0.25 EU\/mL\u003c\/li\u003e\n\u003cli\u003eDocumentation: Experimental conditions for QC tests\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eReporter Virus Construction:\u003c\/b\u003e Reporter protein coding sequences were inserted between the capsid and PE2 loci and contain the 2A-like protease sequence from the Thosea asigna virus (TaV site) at the 3’ end. Upon polyprotein translation in infected cells, the capsid autoprotease domain and the TaV protease cleave the reporter protein from the capsid, resulting in reporter expression independent of incorporation into the virus particle. For additional information, see \u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3911548\/\"\u003ereference\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eShipping:\u003c\/b\u003e As this product is a Sindbis virus strain, customers must submit a USDA APHIS permit VS 16-3 to Advanced Virology prior to order shipment. The permit and additional information are available at \u003ca href=\"https:\/\/www.aphis.usda.gov\/animal-product-import\/organisms-vectors\"\u003eUSDA APHIS Permits\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003e\u003cu\u003eProduction Batch Information links (downloadable):\u003c\/u\u003e\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VR-017_-_Certificate_of_Analysis_-_Signed.pdf?v=1781020690\" target=\"_blank\" rel=\"noopener\"\u003eCertificate of Analysis\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VR-017_-_Sequencing_Results.pdf?v=1781020691\" target=\"_blank\" rel=\"noopener\"\u003eNGS Results and Complete Genome Sequence\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VR-017_-_Batch_Record.pdf?v=1781020692\" target=\"_blank\" rel=\"noopener\"\u003eBatch Record: Detailed Production and QC Data\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV_Product_Use_Policy_04.10.2025.pdf.pdf?v=1746046086\" target=\"_blank\"\u003eProduct Use Policy and Material Transfer Agreement\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Formats:\u003c\/b\u003e This product can be made as a purified or inactivated virus stock, or as purified viral genomic material. Many different reporter proteins and molecular tags can be incorporated. \u003ca href=\"https:\/\/advancedvirology.com\/pages\/made-to-order-viruses\"\u003eCustom variant design and production services\u003c\/a\u003e are also available. Please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e for additional information.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Strains:\u003c\/b\u003e If you require a strain of this virus not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e. We can produce a wide range of common strains to meet your needs.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Viruses Available:\u003c\/b\u003e If you are looking for a virus species or strain not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e with your request. Our team of experts will work with you to create the product that meets your research needs and budget.\u003c\/p\u003e","brand":"Advanced Virology Inc.","offers":[{"title":"Default Title","offer_id":43963665612915,"sku":"AV-VR-017","price":500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/Alphavirus_-_mCherry_Reporter.png?v=1764690198"},{"product_id":"sindbis-virus-strain-tr339-nluc-reporter","title":"Sindbis virus strain TR339 - nLuc Reporter","description":"\u003cp\u003e\u003cb\u003eDescription:\u003c\/b\u003e This alphavirus expresses the reporter protein nanoluciferase (nLuc) at very high levels with minimal effect on viral replication or virulence.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eStrain History:\u003c\/b\u003e TR339 is the consensus wild-type strain of Sindbis virus (SINV) derived from the prototype AR339 isolate (\u003ci\u003eCulex\u003c\/i\u003e spp. mosquitoes, Egypt, 1952). The genomic sequence is \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nuccore\/2628941972\"\u003eavailable in NCBI\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003ePassage History:\u003c\/b\u003e Suckling mouse brain (8). References (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/13259009\/\"\u003e1\u003c\/a\u003e) and (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC190027\/\"\u003e2\u003c\/a\u003e)\u003cbr\u003e\u003cbr\u003e\u003cb\u003eProduction:\u003c\/b\u003e Transfection of \u003ci\u003ein vitro\u003c\/i\u003e transcribed viral genomic RNA into baby hamster kidney (BHK) cells. No serial passages performed.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eBiosafety Level:\u003c\/b\u003e 2\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTiter:\u003c\/b\u003e 4.22 x 10\u003csup\u003e7\u003c\/sup\u003e TCID50\/mL on BHK cells.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e 1.0 mL\/vial. Clarified and filtered cell culture supernatant frozen at -80°C. Delivered on dry ice.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eQA\/QC:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eTiter in TCID50\/mL \u003c\/li\u003e\n\u003cli\u003eWhole-genome sequencing by NGS\u003c\/li\u003e\n\u003cli\u003eMycoplasma test by PCR\u003c\/li\u003e\n\u003cli\u003eSterility test for bacterial and fungal contamination\u003c\/li\u003e\n\u003cli\u003eEndotoxin test \u0026lt;0.25 EU\/mL\u003c\/li\u003e\n\u003cli\u003eDocumented expression of nLuc reporter protein\u003c\/li\u003e\n\u003cli\u003eDocumentation: Experimental conditions for QC tests\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eReporter Virus Construction:\u003c\/b\u003e Reporter protein coding sequences were inserted between the capsid and PE2 loci and contain the 2A-like protease sequence from the Thosea asigna virus (TaV site) at the 3’ end. Upon polyprotein translation in infected cells, the capsid autoprotease domain and the TaV protease cleave the reporter protein from the capsid, resulting in reporter expression independent of incorporation into the virus particle. For additional information, see \u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3911548\/\"\u003ereference\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eShipping:\u003c\/b\u003e As this product is a Sindbis virus strain, customers must submit a USDA APHIS permit VS 16-3 to Advanced Virology prior to order shipment. The permit and additional information are available at \u003ca href=\"https:\/\/www.aphis.usda.gov\/animal-product-import\/organisms-vectors\"\u003eUSDA APHIS Permits\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003e\u003cu\u003eProduction Batch Information links (downloadable):\u003c\/u\u003e\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VR-016_-_Certificate_of_Analysis_-_Signed.pdf?v=1781020432\" rel=\"noopener\" target=\"_blank\"\u003eCertificate of Analysis\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca rel=\"noopener\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VR-016_-_Sequencing_Results.pdf?v=1781020432\" target=\"_blank\"\u003eNGS Results and Complete Genome Sequence\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VR-016_-_Batch_Record.pdf?v=1781020433\" target=\"_blank\" rel=\"noopener\"\u003eBatch Record: Detailed Production and QC Data\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV_Product_Use_Policy_04.10.2025.pdf.pdf?v=1746046086\" target=\"_blank\"\u003eProduct Use Policy and Material Transfer Agreement\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Formats:\u003c\/b\u003e This product can be made as a purified or inactivated virus stock, or as purified viral genomic material. Many different reporter proteins and molecular tags can be incorporated. \u003ca href=\"https:\/\/advancedvirology.com\/pages\/made-to-order-viruses\"\u003eCustom variant design and production services\u003c\/a\u003e are also available. Please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e for additional information.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Strains:\u003c\/b\u003e If you require a strain of this virus not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e. We can produce a wide range of common strains to meet your needs.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Viruses Available:\u003c\/b\u003e If you are looking for a virus species or strain not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e with your request. Our team of experts will work with you to create the product that meets your research needs and budget.\u003c\/p\u003e","brand":"Advanced Virology Inc.","offers":[{"title":"Default Title","offer_id":43963665645683,"sku":"AV-VR-016","price":500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/Alphavirus_-_nLuc_Reporter.png?v=1764690198"},{"product_id":"venezuelan-equine-encephalitis-virus-wild-type","title":"Venezuelan Equine Encephalitis virus - Wild-Type","description":"\u003cp\u003e\u003cb\u003eDescription:\u003c\/b\u003e This virus is an alphavirus.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eStrain History:\u003c\/b\u003e TC-83 is a live-attenuated vaccine strain of Venezuelan equine encephalitis virus (VEEV) derived from the virulent clade IA\/B epizootic strain Trinidad donkey (donkey, Trinidad, 1983). The genomic sequence in \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nuccore\/L01443.1\"\u003eavailable in NCBI\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePassage History:\u003c\/b\u003e Guinea pig heart cells (83). Reference (\u003ca href=\"https:\/\/www.cabidigitallibrary.org\/doi\/full\/10.5555\/19612202523\"\u003e1\u003c\/a\u003e).\u003cbr\u003e\u003cbr\u003e\u003cb\u003eProduction:\u003c\/b\u003e Transfection of \u003ci\u003ein vitro\u003c\/i\u003e transcribed viral genomic RNA into baby hamster kidney (BHK) cells. No serial passages performed.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eBiosafety Level:\u003c\/b\u003e 2\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTiter:\u003c\/b\u003e 1.00 x 10\u003csup\u003e9\u003c\/sup\u003e TCID50\/mL on BHK cells.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e 1.0 mL\/vial. Clarified and filtered cell culture supernatant frozen at -80°C. Delivered on dry ice.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eQA\/QC:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eInfectious titer in TCID50\/mL \u003c\/li\u003e\n\u003cli\u003eWhole-genome sequencing by NGS\u003c\/li\u003e\n\u003cli\u003eMycoplasma test by PCR\u003c\/li\u003e\n\u003cli\u003eSterility test for bacterial and fungal contamination\u003c\/li\u003e\n\u003cli\u003eEndotoxin test \u0026lt;0.25 EU\/mL\u003c\/li\u003e\n\u003cli\u003eDocumentation: Experimental conditions for QC tests\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003e\u003cu\u003eProduction Batch Information links (downloadable):\u003c\/u\u003e\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-V-006_-_Certificate_of_Analysis_-_Signed.pdf?v=1781125840\" rel=\"noopener\" target=\"_blank\"\u003eCertificate of Analysis\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca rel=\"noopener\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-V-006_-_Sequencing_Results.pdf?v=1781125840\" target=\"_blank\"\u003eNGS Results and Complete Genome Sequence\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-V-006_-_Batch_Record.pdf?v=1781125840\" target=\"_blank\" rel=\"noopener\"\u003eBatch Record: Detailed Production and QC Data\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV_Product_Use_Policy_04.10.2025.pdf.pdf?v=1746046086\" target=\"_blank\"\u003eProduct Use Policy and Material Transfer Agreement\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Formats:\u003c\/b\u003e This product can be made as a purified or inactivated virus stock, or as purified viral genomic material. Many different reporter proteins and molecular tags can be incorporated. \u003ca href=\"https:\/\/advancedvirology.com\/pages\/made-to-order-viruses\"\u003eCustom variant design and production services\u003c\/a\u003e are also available. Please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e for additional information.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Strains:\u003c\/b\u003e If you require a strain of this virus not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e. We can produce a wide range of common strains to meet your needs.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Viruses Available:\u003c\/b\u003e If you are looking for a virus species or strain not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e with your request. Our team of experts will work with you to create the product that meets your research needs and budget.\u003c\/p\u003e","brand":"Advanced Virology Inc.","offers":[{"title":"Default Title","offer_id":43963665678451,"sku":"AV-V-006","price":450.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/Alphavirus_-_Wild_Type.png?v=1764690198"},{"product_id":"yellow-fever-virus-vaccine-strain-17d-wild-type","title":"Yellow Fever Virus Vaccine Strain 17D- Wild Type","description":"\u003cp\u003e\u003cb\u003eDescription:\u003c\/b\u003e This virus is a flavivirus.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eStrain History:\u003c\/b\u003e 17D-204 is the live-attenuated vaccine strain of yellow fever virus (YFV) derived from the virulent human clinical isolate Asibi strain (Ghana, 1927). The genomic sequence is \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nucleotide\/NC_002031.1\"\u003eavailable in NCBI\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePassage History:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eParental Asibi strain: Rhesus macaque monkeys (53), intermittent passages in \u003cem\u003eAedes aegypti\u003c\/em\u003e mosquitoes (Unknown). References (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC304575\/\"\u003e1\u003c\/a\u003e) and (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8310116\/\"\u003e2\u003c\/a\u003e).\u003c\/li\u003e\n\u003cli\u003e17D-204: Mouse embryo tissue (18), minced whole chick embryo (58), minced whole chick embryo without brain and spinal cord (128). References (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3883177\/\"\u003e3\u003c\/a\u003e) and (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5563254\/\"\u003e4\u003c\/a\u003e),\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eProduction: \u003c\/b\u003eTransfection of \u003ci\u003ein vitro\u003c\/i\u003e transcribed viral genomic RNA into Vero cells. No serial passages performed.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eBiosafety Level:\u003c\/b\u003e 2\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTiter:\u003c\/strong\u003e 6.81 x 10\u003csup\u003e5\u003c\/sup\u003e TCID50\/mL on Vero cells.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e 1.0 mL\/vial. Clarified and filtered cell culture supernatant frozen at -80°C. Delivered on dry ice.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eQA\/QC:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eInfectious titer in TCID50\/mL\u003c\/li\u003e\n\u003cli\u003eWhole-genome sequencing by NGS\u003c\/li\u003e\n\u003cli\u003eMycoplasma test by PCR\u003c\/li\u003e\n\u003cli\u003eSterility test for bacterial and fungal contamination\u003c\/li\u003e\n\u003cli\u003eEndotoxin test \u0026lt;0.25 EU\/mL\u003c\/li\u003e\n\u003cli\u003eDocumentation: Experimental conditions for QC tests\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cbr\u003e\u003cb\u003e\u003cu\u003eProduction Batch Information links (downloadable):\u003c\/u\u003e\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-V-005_-_Certificate_of_Analysis_-_Signed.pdf?v=1781031092\" rel=\"noopener\" target=\"_blank\"\u003eCertificate of Analysis\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca rel=\"noopener\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-V-005_-_Sequencing_Results.pdf?v=1781031092\" target=\"_blank\"\u003eNGS Results and Complete Genome Sequence\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-V-005_-_Batch_Record.pdf?v=1781031092\" rel=\"noopener\" target=\"_blank\"\u003eBatch Record: Detailed Production and QC Data\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV_Product_Use_Policy_04.10.2025.pdf.pdf?v=1746046086\" target=\"_blank\"\u003eProduct Use Policy and Material Transfer Agreement\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Formats:\u003c\/b\u003e This product can be made as a purified or inactivated virus stock, or as purified viral genomic material. Many different reporter proteins and molecular tags can be incorporated. \u003ca href=\"https:\/\/advancedvirology.com\/pages\/made-to-order-viruses\"\u003eCustom variant design and production services\u003c\/a\u003e are also available. Please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e for additional information.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Strains:\u003c\/b\u003e If you require a strain of this virus not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e. We can produce a wide range of common strains to meet your needs.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Viruses Available:\u003c\/b\u003e If you are looking for a virus species or strain not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e with your request. Our team will work with you to create the product that meets your research needs and budget.\u003c\/p\u003e","brand":"Advanced Virology Inc.","offers":[{"title":"Default Title","offer_id":44006786990195,"sku":"AV-V-005","price":500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/Flavivirus_-_Wildtype.png?v=1764689824"},{"product_id":"yellow-fever-virus-strain-17d-egfp-reporter","title":"Yellow Fever virus strain 17D - eGFP Reporter","description":"\u003cp\u003e\u003cb\u003eDescription:\u003c\/b\u003e This flavivirus expresses the reporter protein eGFP.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eStrain History:\u003c\/b\u003e 17D-204 is the live-attenuated vaccine strain of yellow fever virus (YFV) derived from the virulent human clinical isolate Asibi strain (Ghana, 1927). The genomic sequence is \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nucleotide\/NC_002031.1\"\u003eavailable in NCBI\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePassage History:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eParental Asibi strain: Rhesus macaque monkeys (53), intermittent passages in \u003cem\u003eAedes aegypti\u003c\/em\u003e mosquitoes (Unknown). References (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC304575\/\"\u003e1\u003c\/a\u003e) and (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8310116\/\"\u003e2\u003c\/a\u003e).\u003c\/li\u003e\n\u003cli\u003e17D-204: Mouse embryo tissue (18), minced whole chick embryo (58), minced whole chick embryo without brain and spinal cord (128). References (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3883177\/\"\u003e3\u003c\/a\u003e) and (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5563254\/\"\u003e4\u003c\/a\u003e).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eProduction: \u003c\/b\u003eTransfection of \u003ci\u003ein vitro\u003c\/i\u003e transcribed viral genomic RNA into Vero cells. No serial passages performed.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eBiosafety Level:\u003c\/b\u003e 2\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTiter:\u003c\/strong\u003e 6.81 x 10\u003csup\u003e4\u003c\/sup\u003e TCID50\/mL on Vero cells.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e 1.0 mL\/vial. Clarified and filtered cell culture supernatant frozen at -80°C. Delivered on dry ice.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eQA\/QC:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eInfectious titer in TCID50\/mL\u003c\/li\u003e\n\u003cli\u003eWhole-genome sequencing by NGS\u003c\/li\u003e\n\u003cli\u003eMycoplasma test by PCR\u003c\/li\u003e\n\u003cli\u003eSterility test for bacterial and fungal contamination\u003c\/li\u003e\n\u003cli\u003eEndotoxin test \u0026lt;0.25 EU\/mL\u003c\/li\u003e\n\u003cli\u003eDocumentation: Experimental conditions for QC tests.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eReporter Virus Construction:\u003c\/b\u003e Reporter protein coding sequences were inserted between the 5' UTR and the capsid, and contain the first 75 nucleotides of the capsid protein at the 5' end (modified with silent mutations to prevent homologous recombination with the capsid gene) and the 2A-like protease sequence from the Thosea asigna virus (TaV site) at the 3’ end. Upon polyprotein translation in infected cells, the TaV protease cleaves the reporter protein from the capsid, resulting in reporter expression independent of incorporation into the virus particle. For additional information, see \u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7599567\/\"\u003ereference\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e\u003cu\u003eProduction Batch Information links (downloadable):\u003c\/u\u003e\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VR-004_-_Certificate_of_Analysis_-_Signed.pdf?v=1781039370\" rel=\"noopener\" target=\"_blank\"\u003eCertificate of Analysis\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca rel=\"noopener\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VR-004_-_Sequencing_Results.pdf?v=1781039370\" target=\"_blank\"\u003eNGS Results and Complete Genome Sequence\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VR-004_-_Batch_Record.pdf?v=1781039371\" target=\"_blank\" rel=\"noopener\"\u003eBatch Record: Detailed Production and QC Data\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV_Product_Use_Policy_04.10.2025.pdf.pdf?v=1746046086\" target=\"_blank\"\u003eProduct Use Policy and Material Transfer Agreement\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Formats:\u003c\/b\u003e This product can be made as a purified or inactivated virus stock, or as purified viral genomic material. Many different reporter proteins and molecular tags can be incorporated. \u003ca href=\"https:\/\/advancedvirology.com\/pages\/made-to-order-viruses\"\u003eCustom variant design and production services\u003c\/a\u003e are also available. Please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e for additional information.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Strains:\u003c\/b\u003e If you require a strain of this virus not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e. We can produce a wide range of common strains to meet your needs.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Viruses Available:\u003c\/b\u003e If you are looking for a virus species or strain not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e with your request. Our team will work with you to create the product that meets your research needs and budget.\u003c\/p\u003e","brand":"Advanced Virology Inc.","offers":[{"title":"Default Title","offer_id":44006787055731,"sku":"AV-VR-004","price":550.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/Flavivirus_-_Chimeric_and_Repoter_eGFP.png?v=1764689824"},{"product_id":"yellow-fever-virus-strain-17d-nluc-reporter","title":"Yellow Fever virus strain 17D - nLuc Reporter","description":"\u003cp\u003e\u003cb\u003eDescription:\u003c\/b\u003e This flavivirus expresses the reporter protein nano Luciferase (nLuc).\u003cbr\u003e\u003cbr\u003e\u003cb\u003eStrain History:\u003c\/b\u003e 17D-204 is the live-attenuated vaccine strain of yellow fever virus (YFV) derived from the virulent human clinical isolate Asibi strain (Ghana, 1927). The genomic sequence is \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nucleotide\/NC_002031.1\"\u003eavailable in NCBI\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePassage History:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eParental Asibi strain: Rhesus macaque monkeys (53), intermittent passages in \u003cem\u003eAedes aegypti\u003c\/em\u003e mosquitoes (Unknown). References (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC304575\/\"\u003e1\u003c\/a\u003e) and (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8310116\/\"\u003e2\u003c\/a\u003e).\u003c\/li\u003e\n\u003cli\u003e17D-204: Mouse embryo tissue (18), minced whole chick embryo (58), minced whole chick embryo without brain and spinal cord (128). References (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3883177\/\"\u003e3\u003c\/a\u003e) and (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5563254\/\"\u003e4\u003c\/a\u003e).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eProduction: \u003c\/b\u003eTransfection of \u003ci\u003ein vitro\u003c\/i\u003e transcribed viral genomic RNA into Vero cells. No serial passages performed.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eBiosafety Level:\u003c\/b\u003e 2\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTiter:\u003c\/strong\u003e 2.37 x 10\u003csup\u003e5\u003c\/sup\u003e TCID50\/mL on Vero cells.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e 1.0 mL\/vial. Clarified and filtered cell culture supernatant frozen at -80°C. Delivered on dry ice.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eQA\/QC:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eInfectious titer in TCID50\/mL\u003c\/li\u003e\n\u003cli\u003eWhole-genome sequencing by NGS\u003c\/li\u003e\n\u003cli\u003eMycoplasma test by PCR\u003c\/li\u003e\n\u003cli\u003eSterility test for bacterial and fungal contamination\u003c\/li\u003e\n\u003cli\u003eEndotoxin test \u0026lt;0.25 EU\/mL\u003c\/li\u003e\n\u003cli\u003eDocumented expression of nLuc reporter protein\u003c\/li\u003e\n\u003cli\u003eDocumentation: Experimental conditions for QC tests.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eReporter Virus Construction:\u003c\/b\u003e Reporter protein coding sequences were inserted between the 5' UTR and the capsid, and contain the first 75 nucleotides of the capsid protein at the 5' end (modified with silent mutations to prevent homologous recombination with the capsid gene) and the 2A-like protease sequence from the Thosea asigna virus (TaV site) at the 3’ end. Upon polyprotein translation in infected cells, the TaV protease cleaves the reporter protein from the capsid, resulting in reporter expression independent of incorporation into the virus particle. For additional information, see \u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7599567\/\"\u003ereference\u003c\/a\u003e.\u003cbr\u003e\u003cbr\u003e\u003cb\u003e\u003cu\u003eProduction Batch Information links (downloadable):\u003c\/u\u003e\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VR-005_-_Certificate_of_Analysis_-_Signed.pdf?v=1781039766\" rel=\"noopener\" target=\"_blank\"\u003eCertificate of Analysis\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/Placeholder_PDF_for_product_pages_1.pdf?v=1779819181\" target=\"_blank\"\u003eNGS Results and Complete Genome Sequence\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca rel=\"noopener\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VR-005_-_Batch_Record.pdf?v=1781039766\" target=\"_blank\"\u003eBatch Record: Detailed Production and QC Data\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV_Product_Use_Policy_04.10.2025.pdf.pdf?v=1746046086\" target=\"_blank\"\u003eProduct Use Policy and Material Transfer Agreement\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Formats:\u003c\/b\u003e This product can be made as a purified or inactivated virus stock, or as purified viral genomic material. Many different reporter proteins and molecular tags can be incorporated. \u003ca href=\"https:\/\/advancedvirology.com\/pages\/made-to-order-viruses\"\u003eCustom variant design and production services\u003c\/a\u003e are also available. Please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e for additional information.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Strains:\u003c\/b\u003e If you require a strain of this virus not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e. We can produce a wide range of common strains to meet your needs.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Viruses Available:\u003c\/b\u003e If you are looking for a virus species or strain not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e with your request. Our team will work with you to create the product that meets your research needs and budget.\u003c\/p\u003e","brand":"Advanced Virology Inc.","offers":[{"title":"Default Title","offer_id":44006787088499,"sku":"AV-VR-005","price":550.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/Flavivirus_-_Chimeric_and_Repoter_nLuc.png?v=1764689824"},{"product_id":"zika-virus-strain-paraiba-wild-type","title":"Zika virus strain Paraiba - Wild Type","description":"\u003cp\u003e\u003cb\u003eDescription:\u003c\/b\u003e This virus is a wild-type flavivirus\u003cbr\u003e\u003cbr\u003e\u003cb\u003eStrain History:\u003c\/b\u003e Zika virus (ZIKV) Asian\/American lineage strain Paraíba_01\/2015 was isolated from the serum of an infected human in Brazil in 2015. The genomic sequence in \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nuccore\/KX280026.1\"\u003eavailable in NCBI\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePassage History: \u003c\/b\u003eVero (2). Reference (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4999549\/\"\u003e1\u003c\/a\u003e).\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eProduction: \u003c\/b\u003eTransfection of plasmid encoding the DNA-launched viral genome into Vero cells. No serial passages performed.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eBiosafety Level:\u003c\/b\u003e 2\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTiter:\u003c\/strong\u003e 2.08 x 10\u003csup\u003e4\u003c\/sup\u003e TCID50\/mL on Vero cells.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e 1.0 mL\/vial. Clarified and filtered cell culture supernatant frozen at -80°C. Delivered on dry ice.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eQA\/QC:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eInfectious titer in TCID50\/mL\u003c\/li\u003e\n\u003cli\u003eWhole-genome sequencing by NGS\u003c\/li\u003e\n\u003cli\u003eMycoplasma test by PCR\u003c\/li\u003e\n\u003cli\u003eSterility test for bacterial and fungal contamination\u003c\/li\u003e\n\u003cli\u003eEndotoxin test \u0026lt;0.25 EU\/mL\u003c\/li\u003e\n\u003cli\u003eDocumentation: Experimental conditions for QC tests\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cbr\u003e\u003cb\u003e\u003cu\u003eProduction Batch Information links (downloadable):\u003c\/u\u003e\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-V-003_-_Certificate_of_Analysis_-_Signed.pdf?v=1781011323\" rel=\"noopener\" target=\"_blank\"\u003eCertificate of Analysis\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca rel=\"noopener\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-V-003_-_Sequencing_Results.pdf?v=1781011323\" target=\"_blank\"\u003eNGS Results and Complete Genome Sequence\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-V-003_-_Batch_Record.pdf?v=1781011324\" target=\"_blank\" rel=\"noopener\"\u003eBatch Record: Detailed Production and QC Data\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV_Product_Use_Policy_04.10.2025.pdf.pdf?v=1746046086\" target=\"_blank\"\u003eProduct Use Policy and Material Transfer Agreement\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Formats:\u003c\/b\u003e This product can be made as a purified or inactivated virus stock, or as purified viral genomic material. Many different reporter proteins and molecular tags can be incorporated. \u003ca href=\"https:\/\/advancedvirology.com\/pages\/made-to-order-viruses\"\u003eCustom variant design and production services\u003c\/a\u003e are also available. Please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e for additional information.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Strains:\u003c\/b\u003e If you require a strain of this virus not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e. We can produce a wide range of common strains to meet your needs.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Viruses Available:\u003c\/b\u003e If you are looking for a virus species or strain not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e with your request. Our team will work with you to create the product that meets your research needs and budget.\u003c\/p\u003e","brand":"Advanced Virology Inc.","offers":[{"title":"Default Title","offer_id":44006787317875,"sku":"AV-V-003","price":500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/Flavivirus_-_Wildtype.png?v=1764689824"},{"product_id":"zika-virus-strain-rio-grande-do-norte-natal-wild-type","title":"Zika virus strain Rio Grande do Norte Natal - Wild Type","description":"\u003cp\u003e\u003cb\u003eDescription:\u003c\/b\u003e This virus is a wild-type flavivirus.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eStrain History:\u003c\/b\u003e Zika virus (ZIKV) Asian\/American lineage strain Rio Grande do Norte Natal (RGN) was sequenced directly from the infected brain tissue of a human case of fatal fetal microcephaly contracted in Brazil in 2015. The genomic sequence is \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nuccore\/KU527068.1\"\u003eavailable in NCBI\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePassage History:\u003c\/b\u003e Isolated directly from fetal brain tissue. Reference (\u003ca href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa1600651\"\u003e1\u003c\/a\u003e).\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eProduction: \u003c\/b\u003eTransfection of plasmid encoding the DNA-launched viral genome into Vero cells. No serial passages performed.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eBiosafety Level:\u003c\/b\u003e 2\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTiter:\u003c\/strong\u003e 4.22 x 10\u003csup\u003e6\u003c\/sup\u003e TCID50\/mL on Vero cells.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e 1.0 mL\/vial. Clarified and filtered cell culture supernatant frozen at -80°C. Delivered on dry ice.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eQA\/QC:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eInfectious titer in TCID50\/mL\u003c\/li\u003e\n\u003cli\u003eWhole-genome sequencing by NGS\u003c\/li\u003e\n\u003cli\u003eMycoplasma test by PCR\u003c\/li\u003e\n\u003cli\u003eSterility test for bacterial and fungal contamination\u003c\/li\u003e\n\u003cli\u003eEndotoxin test \u0026lt;0.25 EU\/mL\u003c\/li\u003e\n\u003cli\u003eDocumentation: Experimental conditions for QC tests\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cbr\u003e\u003cb\u003e\u003cu\u003eProduction Batch Information links (downloadable):\u003c\/u\u003e\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003ca rel=\"noopener\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-V-002_-_Certificate_of_Analysis_-_Signed.pdf?v=1780953880\" target=\"_blank\"\u003eCertificate of Analysis\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-V-002_-_Sequencing_Results.pdf?v=1780953880\" rel=\"noopener\" target=\"_blank\"\u003eNGS Results and Complete Genome Sequence\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca rel=\"noopener\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-V-002_Batch_Record.pdf?v=1780953881\" target=\"_blank\"\u003eBatch Record: Detailed Production and QC Data\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV_Product_Use_Policy_04.10.2025.pdf.pdf?v=1746046086\" target=\"_blank\"\u003eProduct Use Policy and Material Transfer Agreement\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Formats:\u003c\/b\u003e This product can be made as a purified or inactivated virus stock, or as purified viral genomic material. Many different reporter proteins and molecular tags can be incorporated. \u003ca href=\"https:\/\/advancedvirology.com\/pages\/made-to-order-viruses\"\u003eCustom variant design and production services\u003c\/a\u003e are also available. Please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e for additional information.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Strains:\u003c\/b\u003e If you require a strain of this virus not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e. We can produce a wide range of common strains to meet your needs.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Viruses Available:\u003c\/b\u003e If you are looking for a virus species or strain not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e with your request. Our team will work with you to create the product that meets your research needs and budget.\u003c\/p\u003e","brand":"Advanced Virology Inc.","offers":[{"title":"Default Title","offer_id":44006790758515,"sku":"AV-V-002","price":500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/Flavivirus_-_Wildtype.png?v=1764689824"},{"product_id":"yellow-fever-virus-strain-17d-mcherry-reporter","title":"Yellow Fever virus strain 17D - mCherry Reporter","description":"\u003cp\u003e\u003cb\u003eDescription:\u003c\/b\u003e This flavivirus expresses the reporter protein mCherry.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eStrain History:\u003c\/b\u003e 17D-204 is the live-attenuated vaccine strain of yellow fever virus (YFV) derived from the virulent human clinical isolate Asibi strain (Ghana, 1927). The genomic sequence is \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nucleotide\/NC_002031.1\"\u003eavailable in NCBI\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePassage History:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eParental Asibi strain: Rhesus macaque monkeys (53), intermittent passages in \u003cem\u003eAedes aegypti\u003c\/em\u003e mosquitoes (Unknown). References (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC304575\/\"\u003e1\u003c\/a\u003e) and (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8310116\/\"\u003e2\u003c\/a\u003e).\u003c\/li\u003e\n\u003cli\u003e17D-204: Mouse embryo tissue (18), minced whole chick embryo (58), minced whole chick embryo without brain and spinal cord (128). References (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3883177\/\"\u003e3\u003c\/a\u003e) and (\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5563254\/\"\u003e4\u003c\/a\u003e).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eProduction: \u003c\/b\u003eTransfection of \u003ci\u003ein vitro\u003c\/i\u003e transcribed viral genomic RNA into Vero cells. No serial passages performed.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eBiosafety Level:\u003c\/b\u003e 2\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTiter:\u003c\/strong\u003e 3.16 x 10\u003csup\u003e6\u003c\/sup\u003e TCID50\/mL on Vero cells.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e 1.0 mL\/vial. Clarified and filtered cell culture supernatant frozen at -80°C. Delivered on dry ice.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eQA\/QC:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eInfectious titer in TCID50\/mL\u003c\/li\u003e\n\u003cli\u003eWhole-genome sequencing by NGS\u003c\/li\u003e\n\u003cli\u003eMycoplasma test by PCR\u003c\/li\u003e\n\u003cli\u003eSterility test for bacterial and fungal contamination\u003c\/li\u003e\n\u003cli\u003eEndotoxin test \u0026lt;0.25 EU\/mL\u003c\/li\u003e\n\u003cli\u003eDocumentation: Experimental conditions for QC tests.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eReporter Virus Construction:\u003c\/b\u003e Reporter protein coding sequences were inserted between the 5' UTR and the capsid, and contain the first 75 nucleotides of the capsid protein at the 5' end (modified with silent mutations to prevent homologous recombination with the capsid gene) and the 2A-like protease sequence from the Thosea asigna virus (TaV site) at the 3’ end. Upon polyprotein translation in infected cells, the TaV protease cleaves the reporter protein from the capsid, resulting in reporter expression independent of incorporation into the virus particle. For additional information, see \u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7599567\/\"\u003ereference\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e\u003cu\u003eProduction Batch Information links (downloadable):\u003c\/u\u003e\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003ca rel=\"noopener\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VR-006_-_Certificate_of_Analysis_-_Signed.pdf?v=1781040150\" target=\"_blank\"\u003eCertificate of Analysis\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VR-006_-_Sequencing_Results.pdf?v=1781040150\" rel=\"noopener\" target=\"_blank\"\u003eNGS Results and Complete Genome Sequence\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca rel=\"noopener\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VR-006_-_Batch_Record.pdf?v=1781040150\" target=\"_blank\"\u003eBatch Record: Detailed Production and QC Data\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV_Product_Use_Policy_04.10.2025.pdf.pdf?v=1746046086\" target=\"_blank\"\u003eProduct Use Policy and Material Transfer Agreement\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Formats:\u003c\/b\u003e This product can be made as a purified or inactivated virus stock, or as purified viral genomic material. Many different reporter proteins and molecular tags can be incorporated. \u003ca href=\"https:\/\/advancedvirology.com\/pages\/made-to-order-viruses\"\u003eCustom variant design and production services\u003c\/a\u003e are also available. Please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e for additional information.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Strains:\u003c\/b\u003e If you require a strain of this virus not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e. We can produce a wide range of common strains to meet your needs.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Viruses Available:\u003c\/b\u003e If you are looking for a virus species or strain not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e with your request. Our team will work with you to create the product that meets your research needs and budget.\u003c\/p\u003e","brand":"Advanced Virology Inc.","offers":[{"title":"Default Title","offer_id":45087935037555,"sku":"AV-VR-006","price":550.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/Untitled-1Yellow_Fever_virus_strain_17D_-_mCherry_Reporter_5e3e3041-0607-486c-a9a9-aff0fcdcc26f.jpg?v=1782134752"},{"product_id":"venezuelan-equine-encephalitis-virus-egfp-reporter","title":"Venezuelan Equine Encephalitis virus - eGFP Reporter","description":"\u003cp\u003e\u003cb\u003eDescription:\u003c\/b\u003e This alphavirus expresses the reporter protein eGFP at very high levels with minimal effect on viral replication or virulence.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eStrain History:\u003c\/b\u003e TC-83 is a live-attenuated vaccine strain of Venezuelan equine encephalitis virus (VEEV) derived from the virulent clade IA\/B epizootic strain Trinidad donkey (donkey, Trinidad, 1983). The genomic sequence in \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nuccore\/L01443.1\"\u003eavailable in NCBI\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePassage History:\u003c\/b\u003e Guinea pig heart cells (83). Reference (\u003ca href=\"https:\/\/www.cabidigitallibrary.org\/doi\/full\/10.5555\/19612202523\"\u003e1\u003c\/a\u003e).\u003cbr\u003e\u003cbr\u003e\u003cb\u003eProduction:\u003c\/b\u003e Transfection of \u003ci\u003ein vitro\u003c\/i\u003e transcribed viral genomic RNA into baby hamster kidney (BHK) cells. No serial passages performed.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eBiosafety Level:\u003c\/b\u003e 2\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTiter:\u003c\/b\u003e 1.00 x 10\u003csup\u003e9\u003c\/sup\u003e TCID50\/mL on BHK cells.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e 1.0 mL\/vial. Clarified and filtered cell culture supernatant frozen at -80°C. Delivered on dry ice.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eQA\/QC:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eInfectious titer in TCID50\/mL \u003c\/li\u003e\n\u003cli\u003eWhole-genome sequencing by NGS\u003c\/li\u003e\n\u003cli\u003eMycoplasma test by PCR\u003c\/li\u003e\n\u003cli\u003eSterility test for bacterial and fungal contamination\u003c\/li\u003e\n\u003cli\u003eEndotoxin test \u0026lt;0.25 EU\/mL\u003c\/li\u003e\n\u003cli\u003eDocumentation: Experimental conditions for QC tests\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eReporter Virus Construction:\u003c\/b\u003e Reporter protein coding sequences were inserted between the capsid and PE2 loci and contain the 2A-like protease sequence from the Thosea asigna virus (TaV site) at the 3’ end. Upon polyprotein translation in infected cells, the capsid autoprotease domain and the TaV protease cleave the reporter protein from the capsid, resulting in reporter expression independent of incorporation into the virus particle. For additional information, see \u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3911548\/\"\u003ereference\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e\u003cu\u003eProduction Batch Information links (downloadable):\u003c\/u\u003e\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003ca rel=\"noopener\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VR-007_-_Certificate_of_Analysis_-_Signed.pdf?v=1781126077\" target=\"_blank\"\u003eCertificate of Analysis\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VR-007_-_Sequencing_Results.pdf?v=1781126077\" rel=\"noopener\" target=\"_blank\"\u003eNGS Results and Complete Genome Sequence\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca rel=\"noopener\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VR-007_-_Batch_Record.pdf?v=1781126078\" target=\"_blank\"\u003eBatch Record: Detailed Production and QC Data\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV_Product_Use_Policy_04.10.2025.pdf.pdf?v=1746046086\" target=\"_blank\"\u003eProduct Use Policy and Material Transfer Agreement\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Formats:\u003c\/b\u003e This product can be made as a purified or inactivated virus stock, or as purified viral genomic material. Many different reporter proteins and molecular tags can be incorporated. \u003ca href=\"https:\/\/advancedvirology.com\/pages\/made-to-order-viruses\"\u003eCustom variant design and production services\u003c\/a\u003e are also available. Please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e for additional information.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Strains:\u003c\/b\u003e If you require a strain of this virus not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e. We can produce a wide range of common strains to meet your needs.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Viruses Available:\u003c\/b\u003e If you are looking for a virus species or strain not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e with your request. Our team of experts will work with you to create the product that meets your research needs and budget.\u003c\/p\u003e","brand":"Advanced Virology Inc.","offers":[{"title":"Default Title","offer_id":45089825194099,"sku":"AV-VR-007","price":500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/Alphavirus_-_eGFP_Reporter.png?v=1764690198"},{"product_id":"venezuelan-equine-encephalitis-virus-nluc-reporter","title":"Venezuelan Equine Encephalitis virus - nLuc Reporter","description":"\u003cp\u003e\u003cb\u003eDescription:\u003c\/b\u003e This alphavirus expresses the reporter protein nLuc at very high levels with minimal effect on viral replication or virulence.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eStrain History:\u003c\/b\u003e TC-83 is a live-attenuated vaccine strain of Venezuelan equine encephalitis virus (VEEV) derived from the virulent clade IA\/B epizootic strain Trinidad donkey (donkey, Trinidad, 1983). The genomic sequence in \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nuccore\/L01443.1\"\u003eavailable in NCBI\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePassage History:\u003c\/b\u003e Guinea pig heart cells (83). Reference (\u003ca href=\"https:\/\/www.cabidigitallibrary.org\/doi\/full\/10.5555\/19612202523\"\u003e1\u003c\/a\u003e).\u003cbr\u003e\u003cbr\u003e\u003cb\u003eProduction:\u003c\/b\u003e Transfection of \u003ci\u003ein vitro\u003c\/i\u003e transcribed viral genomic RNA into baby hamster kidney (BHK) cells. No serial passages performed.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eBiosafety Level:\u003c\/b\u003e 2\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTiter:\u003c\/b\u003e 1.00 x 10\u003csup\u003e9\u003c\/sup\u003e TCID50\/mL on BHK cells.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e 1.0 mL\/vial. Clarified and filtered cell culture supernatant frozen at -80°C. Delivered on dry ice.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eQA\/QC:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eInfectious titer in TCID50\/mL \u003c\/li\u003e\n\u003cli\u003eWhole-genome sequencing by NGS\u003c\/li\u003e\n\u003cli\u003eMycoplasma test by PCR\u003c\/li\u003e\n\u003cli\u003eSterility test for bacterial and fungal contamination\u003c\/li\u003e\n\u003cli\u003eEndotoxin test \u0026lt;0.25 EU\/mL\u003c\/li\u003e\n\u003cli\u003eDocumentation: Experimental conditions for QC tests\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eReporter Virus Construction:\u003c\/b\u003e Reporter protein coding sequences were inserted between the capsid and PE2 loci and contain the 2A-like protease sequence from the Thosea asigna virus (TaV site) at the 3’ end. Upon polyprotein translation in infected cells, the capsid autoprotease domain and the TaV protease cleave the reporter protein from the capsid, resulting in reporter expression independent of incorporation into the virus particle. For additional information, see \u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3911548\/\"\u003ereference\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e\u003cu\u003eProduction Batch Information links (downloadable):\u003c\/u\u003e\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VR-008_-_Certificate_of_Analysis_-_Signed.pdf?v=1781126475\" rel=\"noopener\" target=\"_blank\"\u003eCertificate of Analysis\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca rel=\"noopener\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VR-008_-_Sequencing_Results.pdf?v=1781126475\" target=\"_blank\"\u003eNGS Results and Complete Genome Sequence\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VR-008_-_Batch_Record.pdf?v=1781126476\" target=\"_blank\" rel=\"noopener\"\u003eBatch Record: Detailed Production and QC Data\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV_Product_Use_Policy_04.10.2025.pdf.pdf?v=1746046086\" target=\"_blank\"\u003eProduct Use Policy and Material Transfer Agreement\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Formats:\u003c\/b\u003e This product can be made as a purified or inactivated virus stock, or as purified viral genomic material. Many different reporter proteins and molecular tags can be incorporated. \u003ca href=\"https:\/\/advancedvirology.com\/pages\/made-to-order-viruses\"\u003eCustom variant design and production services\u003c\/a\u003e are also available. Please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e for additional information.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Strains:\u003c\/b\u003e If you require a strain of this virus not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e. We can produce a wide range of common strains to meet your needs.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Viruses Available:\u003c\/b\u003e If you are looking for a virus species or strain not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e with your request. Our team of experts will work with you to create the product that meets your research needs and budget.\u003c\/p\u003e","brand":"Advanced Virology Inc.","offers":[{"title":"Default Title","offer_id":45089936244851,"sku":"AV-VR-008","price":500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/Alphavirus_-_nLuc_Reporter.png?v=1764690198"},{"product_id":"venezuelan-equine-encephalitis-virus-mcherry-reporter","title":"Venezuelan Equine Encephalitis virus - mCherry Reporter","description":"\u003cp\u003e\u003cb\u003eDescription:\u003c\/b\u003e This alphavirus expresses the reporter protein mCherry at very high levels with minimal effect on viral replication or virulence.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eStrain History:\u003c\/b\u003e TC-83 is a live-attenuated vaccine strain of Venezuelan equine encephalitis virus (VEEV) derived from the virulent clade IA\/B epizootic strain Trinidad donkey (donkey, Trinidad, 1983). The genomic sequence in \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/nuccore\/L01443.1\"\u003eavailable in NCBI\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePassage History:\u003c\/b\u003e Guinea pig heart cells (83). Reference (\u003ca href=\"https:\/\/www.cabidigitallibrary.org\/doi\/full\/10.5555\/19612202523\"\u003e1\u003c\/a\u003e).\u003cbr\u003e\u003cbr\u003e\u003cb\u003eProduction:\u003c\/b\u003e Transfection of \u003ci\u003ein vitro\u003c\/i\u003e transcribed viral genomic RNA into baby hamster kidney (BHK) cells. No serial passages performed.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eBiosafety Level:\u003c\/b\u003e 2\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTiter:\u003c\/b\u003e 1.00 x 10\u003csup\u003e9\u003c\/sup\u003e TCID50\/mL on BHK cells.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e 1.0 mL\/vial. Clarified and filtered cell culture supernatant frozen at -80°C. Delivered on dry ice.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eQA\/QC:\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eInfectious titer in TCID50\/mL \u003c\/li\u003e\n\u003cli\u003eWhole-genome sequencing by NGS\u003c\/li\u003e\n\u003cli\u003eMycoplasma test by PCR\u003c\/li\u003e\n\u003cli\u003eSterility test for bacterial and fungal contamination\u003c\/li\u003e\n\u003cli\u003eEndotoxin test \u0026lt;0.25 EU\/mL\u003c\/li\u003e\n\u003cli\u003eDocumentation: Experimental conditions for QC tests\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eReporter Virus Construction:\u003c\/b\u003e Reporter protein coding sequences were inserted between the capsid and PE2 loci and contain the 2A-like protease sequence from the Thosea asigna virus (TaV site) at the 3’ end. Upon polyprotein translation in infected cells, the capsid autoprotease domain and the TaV protease cleave the reporter protein from the capsid, resulting in reporter expression independent of incorporation into the virus particle. For additional information, see \u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3911548\/\"\u003ereference\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e\u003cu\u003eProduction Batch Information links (downloadable):\u003c\/u\u003e\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VR-009_-_Certificate_of_Analysis_-_Signed.pdf?v=1781126613\" rel=\"noopener\" target=\"_blank\"\u003eCertificate of Analysis\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca rel=\"noopener\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VR-009_-_Sequencing_Results.pdf?v=1781126613\" target=\"_blank\"\u003eNGS Results and Complete Genome Sequence\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV-VR-009_-_Batch_Record.pdf?v=1781126613\" target=\"_blank\" rel=\"noopener\"\u003eBatch Record: Detailed Production and QC Data\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/AV_Product_Use_Policy_04.10.2025.pdf.pdf?v=1746046086\" target=\"_blank\"\u003eProduct Use Policy and Material Transfer Agreement\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Formats:\u003c\/b\u003e This product can be made as a purified or inactivated virus stock, or as purified viral genomic material. Many different reporter proteins and molecular tags can be incorporated. \u003ca href=\"https:\/\/advancedvirology.com\/pages\/made-to-order-viruses\"\u003eCustom variant design and production services\u003c\/a\u003e are also available. Please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e for additional information.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Strains:\u003c\/b\u003e If you require a strain of this virus not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e. We can produce a wide range of common strains to meet your needs.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAdditional Viruses Available:\u003c\/b\u003e If you are looking for a virus species or strain not listed on our website, please \u003ca href=\"https:\/\/advancedvirology.com\/pages\/contact-us\"\u003econtact us\u003c\/a\u003e with your request. Our team of experts will work with you to create the product that meets your research needs and budget.\u003c\/p\u003e","brand":"Advanced Virology Inc.","offers":[{"title":"Default Title","offer_id":45090006368371,"sku":"AV-VR-009","price":500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0615\/7018\/7379\/files\/Alphavirus_-_mCherry_Reporter.png?v=1764690198"}],"url":"https:\/\/advancedvirology.com\/collections\/in-stock.oembed?page=2","provider":"Advanced Virology Inc.","version":"1.0","type":"link"}