• Verified Academic Customers Receive 60% OFF to Support Research

ABOUT ADVANCED VIROLOGY INC.

Driving Innovation
in Virology

Advanced Virology Inc. is a specialized biotechnology and virology company that develops cutting-edge plasmid-based reverse genetics systems, and uses them to manufacture and supply high-fidelity virus stocks, reporter viruses, viral genomic material, custom mutants and other custom virus products and solutions for biotechs developing vaccines and antivirals, pharmaceutical manufacturers, diagnostics assay developers and providers, and academic, non-profit and government research institutions.

Founded in 2022, Advanced Virology is headquartered in Athens, Ohio and operates a BSL-2 R&D and production laboratory. Our team combines over 80 years of virology and molecular biology expertise to support vaccine development, drug discovery, diagnostics assay R&D and academic virology research worldwide.

OUR MISSION & VISION

We aim to lead globally in virology, delivering high-purity viral solutions that drive vaccines, gene therapies, and antiviral treatments. Through innovation and collaboration, we bridge research and clinical applications to advance disease control and immunotherapy.

CERTIFICATIONS & COMPLIANCE

Commitment to Safety & Regulatory Excellence

We adhere to the most stringent industry standards to ensure the reliability and safety of our viral products:

  •  
  • BSL-2 Certified Facilities: Ensuring controlled, safe virus handling.

  • Regulatory Excellence: Compliance with FDA, CDC, and WHO guidelines for virus production and research applications.

  • Stringent QC Testing: Including titer validation, next-generation sequencing, sterility testing, and endotoxin assessment.

  • Industry Leading Transparency: Unprecedented reporting of virus production and QC testing data for every manufactured virus stock.

What We Do

Custom virus stock design and production using reverse genetics-based methods

Ready-to-ship wild-type virus stocks and reporter viruses

Quality control testing including NGS, sterility, and endotoxin testing

Grant support and regulatory consultation

Large scale virus production - up to 50L per production run

  • De novo production of new virus strain
  • Tailored purification and QC solutions
  • Volume expansion from seed stocks
  • Large scale virus production, up to 50L per production run

Who We Serve

Biotechnology companies developing vaccines and antiviral therapeutics

Pharmaceutical companies conducting drug discovery

Diagnostic companies developing and testing new assays and requiring viral controls for established assays

Academic and government research institutions performing basic virology research

Order Viruses Online

OUR TEAM

Leaders In Virology
& Biotechnology

At Advanced Virology Inc., our success is built on the expertise, dedication, and collaboration of our team. With a strong foundation in virology, biotechnology and biomanufacturing, we are committed to delivering high-quality viral solutions that drive research and therapeutic advancements. Our approach is defined by:

 

1. Scientific Expertise

The Advanced Virology team consists of academic and industry scientists with over 45 years combined experience in developing reverse genetics systems and producing virus stocks for academic, commercial and government users. Our comprehensive expertise covers most virus families and product types and we specialize in producing difficult to grow virus strains.

2. Commitment to Innovation

Our goal is to lead the industry with exceptionally high-quality virus product manufacturing. To this end, we swiftly incorporate new discoveries and inventions into our virus product manufacturing processes by continuously iterating every stage of virus production and quality control testing. We use the latest advances in reverse genetics, cell modification, assay methods and manufacturing and quality control processes to boost virus product quality and yields to the highest achievable levels.

3. Collaborative Approach

The trust of our customers is of utmost importance to us, as custom virus product manufacturing requires close cooperation with customers. We actively engage with our clients from the very first step to ensure optimal product design and production. For every project, we jointly create a unique timeline with deliverable milestones prior to the initiation of virus production. We provide honest and timely communication at every project milestone to provide our clients with the highest possible value for their trust in us.

Virus Families

1

Alphaviruses

  • Sindbis virus (SINV) strain TR339
  • Chikungunya virus (CHIKV) vaccine strain 181/25
  • Venezuelan equine encephalitis virus (VEEV) strain TC-83
  • Eastern equine encephalitis virus (EEEV)
  • Western equine encephalitis virus (WEEV)
  • Mayaro virus
  • Chimeric alphaviruses
2

Flaviviruses

  • Yellow fever virus (YFV) vaccine strain 17-D
  • Dengue virus (DENV) Type 1 strain Hawaii, Type 2 strains 16681 and New Guinea C, Type 3 strain H87, Type 4 strain
  • West Nile virus (WNV) strain NY99
  • Zika virus (ZIKV) strains Paraiba and Rio Grande do Natal
3

Coronaviruses

  • SARS-CoV-2
  • Human coronaviruses OC43, NL63, 229E, HKU1
4

Influenza virus

  • PR8 strain
  • Seasonal influenza strains
5

Respiratory Syncytial virus (RSV)

  • RSV A Memphis-37 strain
  • RSV A A2 strain
  • RSV A Long strain
  • RSV B9320 strain
6

Human Parainfluenza virus

  • HPIV Type 1
  • HPIV Type 2
  • HPIV Type 3
  • HPIV Type 4
7

Human Metapneumovirus

  • HMPV Type A1
  • HMPV Type A2a
  • HMPV Type A2b
  • HMPV Type B1
  • HMPV Type B2
8

Human norovirus

  • Genogroup GI - multiple
  • Genogroup GII - GII.4 and GII.17 and others
9

Rotavirus

Broad capability across associated strains

10

Measles virus

Broad capability across associated strains

11

Custom

  • We can make any virus you need and specialize in difficult to grow virus strains

Browse Our Ready-To-Ship Viruses

Sindbis (TR339)/Eastern Equine Encephalitis (FL93-939) Chimeric Virus eGFP Reporter

Sindbis (TR339)/Western Equine Encephalitis (McMillan) Chimeric Virus eGFP Reporter

Sindbis (TR339)/Eastern Equine Encephalitis (FL93-939) Chimeric Virus

Venezuelan Equine Encephalitis virus - mCherry Reporter

Venezuelan Equine Encephalitis virus - nLuc Reporter

Venezuelan Equine Encephalitis virus - eGFP Reporter

Yellow Fever virus strain 17D - mCherry Reporter

Zika virus strain Rio Grande do Norte Natal - Wild Type

GRANT SUPPORT SERVICES

Grants & Project
Planning Support

Advanced Virology provides specialized virology expertise and virus production services to support successful grant applications and research project execution.


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Your dedicated partner and technical resource throughout the entire process.

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What Our Customers Are Saying

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What Our
Customers Are Saying

Advanced Virology was extremely responsive and helpful in supplying us with a reporter model system for an Alphavirus, which assisted us in meeting our tight deadlines. Once received, the virus proved to be highly functional, and expression of the reporter gene was achieved by simply following Advanced Virology’s provided protocol. Hats off to the Advanced Virology Team!  

Laura Bronsart, Ambient Biosciences

Working with Advanced Virology was a pleasure. Their team demonstrated deep expertise in both the science and regulatory aspects of reverse engineering and producing recombinant viruses. All of our concerns—ranging from reporter insertion and stability to regulatory compliance—were addressed promptly and thoroughly. The delivery was completed ahead of schedule, making the entire process smooth and efficient. Compared to the complex paperwork required when procuring from academic institutions, Advanced Virology offered a much simpler and more streamlined experience. I would highly recommend their services to others in the field.  

Dr. Rajini Mudhasani, USAMRIID

 

Advanced Virology was phenomenal to work with! The team went above and beyond following up and providing resources. We are excited to incorporate our newly purchased EEEV/SINV chimera into our research.

Athena Chlapowski, Laboratory Manager

CUSTOM ORDER INQUIRY

Let's Create the Right Virus for Your Research

Partner with Advanced Virology Inc. to develop high-quality, custom virus stocks that align with your research goals. Fill out the form below, and our experts will get in touch to discuss your specific needs and project requirements.

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Prefer another way to contact?
Email us : info@advancedvirology.com